iPTMnet Report for Q8WWQ0 (PHIP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WWQ0 / PHIP_HUMAN
Protein Name PH-interacting protein
Gene Name Name: PHIP
Synonyms:DCAF14,WDR11;
Organism Homo sapiens (Human)

PRO ID PR:Q8WWQ0
DAG View
PRO Name PH-interacting protein (human)
Definition A PH-interacting protein that is encoded in the genome of human.
Short Label hPHIP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WWQ0 (PHIP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Ubiquitination PhosphoSitePlus
Y16 Phosphorylation PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
S123 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S136 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
Y140 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S142 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y235 Phosphorylation PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
T423 Phosphorylation PhosphoSitePlus
T438 Phosphorylation PhosphoSitePlus
T441 Phosphorylation PhosphoSitePlus
T447 Phosphorylation PhosphoSitePlus
Y505 Phosphorylation PhosphoSitePlus
S633 Phosphorylation PhosphoSitePlus
S641 Phosphorylation PhosphoSitePlus   UniProt 20068231
S659 Phosphorylation PhosphoSitePlus   UniProt 20068231
S671 Phosphorylation PhosphoSitePlus
R672 Methylation PhosphoSitePlus
S674 Phosphorylation PhosphoSitePlus   UniProt 23186163
S676 Phosphorylation PhosphoSitePlus
S677 Phosphorylation PhosphoSitePlus   UniProt 23186163
S679 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S683 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18220336
S692 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231
S703 Phosphorylation PhosphoSitePlus
K764 Ubiquitination PhosphoSitePlus
K767 Ubiquitination PhosphoSitePlus
S772 O-Glycosylation GlyGen 30379171, 34019948, 29351928
K773 Ubiquitination PhosphoSitePlus
K787 Ubiquitination PhosphoSitePlus
Y796 Phosphorylation PhosphoSitePlus
S879 Phosphorylation PhosphoSitePlus   UniProt 21406692
S880 Phosphorylation PhosphoSitePlus   UniProt 21406692
S881 Phosphorylation PhosphoSitePlus   UniProt 21406692
S911 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18669648, 20068231
K982 Ubiquitination PhosphoSitePlus
Y984 Phosphorylation PhosphoSitePlus
S985 Phosphorylation PhosphoSitePlus
K989 Ubiquitination PhosphoSitePlus
K990 Ubiquitination PhosphoSitePlus
K1005 Ubiquitination PhosphoSitePlus
K1010 Ubiquitination PhosphoSitePlus
Y1011 Phosphorylation PhosphoSitePlus
K1032 Ubiquitination PhosphoSitePlus
K1062 Ubiquitination PhosphoSitePlus
K1150 Ubiquitination PhosphoSitePlus
S1243 Phosphorylation PhosphoSitePlus
S1274 Phosphorylation PhosphoSitePlus
S1281 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 16565220, ...18669648, 19690332
S1283 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 16565220, ...18669648, 19690332
T1295 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1296 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T1297 Phosphorylation phospho.ELM 18669648
S1315 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16565220, ...24275569, 19690332, 20068231
Y1316 Phosphorylation PhosphoSitePlus
T1359 Phosphorylation PhosphoSitePlus   UniProt 20068231
T1369 Phosphorylation PhosphoSitePlus
S1377 Phosphorylation PhosphoSitePlus
K1383 Ubiquitination PhosphoSitePlus
S1390 Phosphorylation phospho.ELM 18669648
S1392 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K1393 Ubiquitination PhosphoSitePlus
T1396 Phosphorylation PhosphoSitePlus
S1398 Phosphorylation PhosphoSitePlus
K1399 Acetylation PhosphoSitePlus
S1405 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 16565220
T1438 O-Glycosylation GlyGen 30379171, 34019948, 29351928
K1443 Acetylation PhosphoSitePlus
S1447 Phosphorylation PhosphoSitePlus
S1448 Phosphorylation PhosphoSitePlus
S1451 Phosphorylation PhosphoSitePlus
S1452 Phosphorylation PhosphoSitePlus
S1453 Phosphorylation PhosphoSitePlus
S1456 Phosphorylation PhosphoSitePlus
S1457 Phosphorylation PhosphoSitePlus
K1461 Acetylation PhosphoSitePlus
K1466 Ubiquitination PhosphoSitePlus
K1470 Sumoylation PhosphoSitePlus
S1471 Phosphorylation PhosphoSitePlus
S1473 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
S1474 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
T1475 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
S1476 Phosphorylation phospho.ELM   PhosphoSitePlus 16565220
S1479 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T1480 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1482 Phosphorylation PhosphoSitePlus
K1497 Acetylation PhosphoSitePlus   UniProt 19608861
K1497 Ubiquitination PhosphoSitePlus
T1498 Phosphorylation PhosphoSitePlus
S1500 Phosphorylation PhosphoSitePlus
S1501 Phosphorylation PhosphoSitePlus
S1502 Phosphorylation PhosphoSitePlus
T1506 Phosphorylation phospho.ELM 18669648
S1508 Phosphorylation PhosphoSitePlus
S1522 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1524 O-Glycosylation GlyGen 32938750
S1525 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K1528 Acetylation PhosphoSitePlus
K1528 Ubiquitination PhosphoSitePlus
K1533 Acetylation PhosphoSitePlus   UniProt 19608861
K1533 Ubiquitination PhosphoSitePlus
K1542 Acetylation PhosphoSitePlus
K1542 Ubiquitination PhosphoSitePlus
S1548 Phosphorylation PhosphoSitePlus
K1550 Ubiquitination PhosphoSitePlus
K1553 Acetylation PhosphoSitePlus
K1553 Ubiquitination PhosphoSitePlus
S1559 Phosphorylation PhosphoSitePlus
S1560 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S1564 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1565 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1567 Phosphorylation phospho.ELM 18669648
T1570 Phosphorylation PhosphoSitePlus
S1591 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S1592 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
K1602 Ubiquitination PhosphoSitePlus
T1649 Phosphorylation PhosphoSitePlus
S1651 Phosphorylation PhosphoSitePlus   UniProt 20068231
S1734 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K1736 Ubiquitination PhosphoSitePlus
K1745 Ubiquitination PhosphoSitePlus
K1760 Ubiquitination PhosphoSitePlus
S1762 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
Y1778 Phosphorylation phospho.ELM 18669648
S1783 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16565220, ...18669648, 19690332, 20068231
S1796 Phosphorylation PhosphoSitePlus
R1804 Methylation PhosphoSitePlus
K1815 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K65 Q65 Biomuta DOID:363 / uterine cancer [ icgc ]
K116 N116 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S142 I142 Biomuta DOID:1324 / lung cancer [ cosmic ]
K367 N367 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K421 Q421 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S674 P674 Biomuta DOID:4159 / skin cancer [ cosmic ]
S676 R676 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K767 N767 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K773 E773 Biomuta DOID:1319 / brain cancer [ icgc ]
S881 L881 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S1243 N1243 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S1274 L1274 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1283 F1283 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1283 T1283 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S1390 C1390 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S1392 F1392 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1461 E1461 Biomuta DOID:4159 / skin cancer [ cosmic ]
K1461 T1461 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1470 I1470 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1476 F1476 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S1502 Y1502 Biomuta DOID:363 / uterine cancer [ icgc ]
T1506 A1506 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1508 N1508 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
S1522 F1522 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ]
K1528 N1528 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S1548 C1548 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1550 R1550 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S1564 Y1564 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1565 T1565 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1567 T1567 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K1602 T1602 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T1649 I1649 Biomuta DOID:1612 / breast cancer [ cosmic ]
T1649 A1649 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K1745 M1745 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K1760 R1760 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ]
S1762 P1762 Biomuta [ cosmic ]
Y1778 H1778 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1783 Y1783 Biomuta DOID:1324 / lung cancer [ cosmic ]
R1804 T1804 Biomuta DOID:1612 / breast cancer [ cosmic ]