iPTMnet Report for Q8WVK2 (SNRNP27)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WVK2 / SNR27_HUMAN
Protein Name U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein
Gene Name Name: SNRNP27
Organism Homo sapiens (Human)

PRO ID PR:Q8WVK2
DAG View
PRO Name U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein (human)
Definition A U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein that is encoded in the genome of human.
Short Label hSNRNP27
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WVK2 (SNRNP27) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 17081983
S8 Phosphorylation HPRD 17081983
S51 Phosphorylation PhosphoSitePlus
S53 Phosphorylation PhosphoSitePlus
S59 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 20068231
T60 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648, 20068231
S61 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 20068231
S63 Phosphorylation HPRD   PhosphoSitePlus 19651622, 20068231
S65 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
S111 Phosphorylation PhosphoSitePlus   UniProt 23186163
S114 Phosphorylation PhosphoSitePlus   UniProt 23186163
S123 Phosphorylation PhosphoSitePlus
Y127 Phosphorylation PhosphoSitePlus
S132 Phosphorylation HPRD   PhosphoSitePlus   UniProt 17525332, 23186163
K134 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S6 I6 Biomuta DOID:3571 / liver cancer [ cosmic ]
S61 P61 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S111 Y111 Biomuta DOID:4159 / skin cancer [ cosmic ]
S123 F123 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]