iPTMnet Report for Q8WUA7 (TBC1D22A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8WUA7 / TB22A_HUMAN
Protein Name TBC1 domain family member 22A
Gene Name Name: TBC1D22A
Synonyms:C22orf4;
Organism Homo sapiens (Human)

PRO ID PR:Q8WUA7
DAG View
PRO Name TBC1 domain family member 22A (human)
Definition A TBC1 domain family member 22A that is encoded in the genome of human.
Short Label hTBC1D22A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8WUA7 (TBC1D22A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 23572552
S16 Phosphorylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus
S44 O-Glycosylation GlyGen 30379171
T50 Phosphorylation PhosphoSitePlus
T51 Phosphorylation IEDB   PhosphoSitePlus 27869121
S132 Phosphorylation PhosphoSitePlus   UniProt 24275569
S143 Phosphorylation PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
T149 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
C151 S-Nitrosylation dbSNO 26338901
S165 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S167 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
T173 Phosphorylation PhosphoSitePlus
T175 Phosphorylation phospho.ELM 18669648
T179 Phosphorylation PhosphoSitePlus
S188 Phosphorylation PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T50 Phosphorylation HPRD 20068231
T51 Phosphorylation HPRD 20068231
S132 Phosphorylation HPRD 19651622
S135 Phosphorylation HPRD 17081983
S165 Phosphorylation HPRD 18669648, 20068231, 20230923
S167 Phosphorylation HPRD 20230923
T175 Phosphorylation HPRD 18669648
S188 Phosphorylation HPRD 20068231
S219 Phosphorylation HPRD 20068231
S221 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S167 C167 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S188 P188 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S221 F221 Biomuta DOID:4159 / skin cancer [ icgc ]
S288 R288 Biomuta DOID:363 / uterine cancer [ icgc ]