iPTMnet Report for Q8WU76 (SCFD2)
Protein Information
| UniProt AC / UniProt ID | Q8WU76 / SCFD2_HUMAN |
| Protein Name | Sec1 family domain-containing protein 2 |
| Gene Name | Name: SCFD2 Synonyms:STXBP1L1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8WU76 |
| PRO Name | Sec1 family domain-containing protein 2 (human) |
| Definition | A Sec1 family domain-containing protein 2 that is encoded in the genome of human. |
| Short Label | hSCFD2 |
| Category | organism-gene |
DAG ViewQ8WU76 (SCFD2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K69 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K82 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C94 | Methylation | score1 | IEDB | 31844290 | ||
| C141 | Methylation | score1 | IEDB | 31844290 | ||
| K196 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C227 | Methylation | score1 | IEDB | 31844290 | ||
| K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S335 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S336 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T338 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T339 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K353 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K375 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S388 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| C404 | Methylation | score1 | IEDB | 31844290 | ||
| K424 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K500 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K534 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K555 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S648 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T653 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K664 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K196 | R196 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
| K196 | N196 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| C227 | G227 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K257 | N257 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| S335 | F335 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T339 | A339 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K375 | T375 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S388 | P388 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S648 | L648 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] |
