iPTMnet Report for Q8WTS6 (SETD7)
Protein Information
UniProt AC / UniProt ID | Q8WTS6 / SETD7_HUMAN |
Protein Name | Histone-lysine N-methyltransferase SETD7 |
Gene Name | Name: SETD7 Synonyms:KIAA1717,KMT7,SET7; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8WTS6 |
PRO Name | histone-lysine N-methyltransferase SETD7 (human) |
Definition | A histone-lysine N-methyltransferase SETD7 that is encoded in the genome of human. |
Short Label | hSETD7 |
Category | organism-gene |
Q8WTS6 (SETD7) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
C26 | Methylation | score1 | IEDB | 31844290 | ||
Y30 | Phosphorylation | score1 | IEDB | 32387766 | ||
K45 | Ubiquitination | score1 | PhosphoSitePlus | |||
K111 | Ubiquitination | score1 | PhosphoSitePlus | |||
R152 | Methylation | score1 | PhosphoSitePlus | |||
K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
S225 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y305 | Phosphorylation | score1 | PhosphoSitePlus | |||
T332 | Phosphorylation | score1 | PhosphoSitePlus | |||
S340 | Phosphorylation | score1 | PhosphoSitePlus | |||
S345 | Phosphorylation | score1 | PhosphoSitePlus | |||
K358 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S3 | R3 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T332 | I332 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |