iPTMnet Report for Q8TF44 (C2CD4C)
Protein Information
UniProt AC / UniProt ID | Q8TF44 / C2C4C_HUMAN |
Protein Name | C2 calcium-dependent domain-containing protein 4C |
Gene Name | Name: C2CD4C Synonyms:FAM148C,KIAA1957,NLF3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TF44 |
PRO Name | C2 calcium-dependent domain-containing protein 4C (human) |
Definition | A C2 calcium-dependent domain-containing protein 4C that is encoded in the genome of human. |
Short Label | hC2CD4C |
Category | organism-gene |
Q8TF44 (C2CD4C) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R22 | Methylation | score1 | PhosphoSitePlus | |||
S33 | Phosphorylation | score1 | PhosphoSitePlus | |||
T86 | Phosphorylation | score1 | PhosphoSitePlus | |||
S89 | Phosphorylation | score1 | PhosphoSitePlus | |||
T146 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y148 | Phosphorylation | score1 | PhosphoSitePlus | |||
S156 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18220336 | ||
S178 | Phosphorylation | score1 | PhosphoSitePlus | |||
S206 | O-Glycosylation | score1 | GlyGen | 29237092 | ||
S206 | Phosphorylation | score1 | PhosphoSitePlus | |||
S229 | Phosphorylation | score1 | PhosphoSitePlus | |||
S237 | Phosphorylation | score1 | PhosphoSitePlus | |||
K240 | Methylation | score1 | PhosphoSitePlus | |||
S256 | Phosphorylation | score1 | PhosphoSitePlus | |||
S262 | Phosphorylation | score1 | PhosphoSitePlus | |||
S264 | Phosphorylation | score1 | PhosphoSitePlus | |||
S273 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
T405 | Phosphorylation | score1 | PhosphoSitePlus | |||
T415 | Phosphorylation | score1 | PhosphoSitePlus | |||
S416 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R22 | W22 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] | |
Y148 | * | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S264 | C264 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S416 | Y416 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |