iPTMnet Report for Q8TEC5 (SH3RF2)
Protein Information
UniProt AC / UniProt ID | Q8TEC5 / SH3R2_HUMAN |
Protein Name | E3 ubiquitin-protein ligase SH3RF2 |
Gene Name | Name: SH3RF2 Synonyms:POSH3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TEC5 |
PRO Name | E3 ubiquitin-protein ligase SH3RF2 (human) |
Definition | An E3 ubiquitin-protein ligase SH3RF2 that is encoded in the genome of human. |
Short Label | hSH3RF2 |
Category | organism-gene |
Q8TEC5 (SH3RF2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R84 | Methylation | score1 | PhosphoSitePlus | |||
S112 | Phosphorylation | score1 | PhosphoSitePlus | |||
K234 | Ubiquitination | score1 | PhosphoSitePlus | |||
T425 | Phosphorylation | score1 | PhosphoSitePlus | |||
S508 | Phosphorylation | score1 | PhosphoSitePlus | |||
T642 | Phosphorylation | score1 | PhosphoSitePlus | |||
S649 | Phosphorylation | score1 | PhosphoSitePlus | |||
T657 | Phosphorylation | score1 | PhosphoSitePlus | |||
S680 | Phosphorylation | score1 | PhosphoSitePlus | |||
T686 | Phosphorylation | score1 | PhosphoSitePlus | |||
S707 | Phosphorylation | score1 | PhosphoSitePlus | |||
T713 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S112 | T112 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
T425 | N425 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
T642 | I642 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S680 | F680 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ icgc ] | |
S707 | P707 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |