iPTMnet Report for Q8TE99 (PXYLP1)
Protein Information
UniProt AC / UniProt ID | Q8TE99 / PXYP1_HUMAN |
Protein Name | 2-phosphoxylose phosphatase 1 |
Gene Name | Name: PXYLP1 Synonyms:ACPL2,HEL124;ORFNames:UNQ370/PRO706; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TE99 |
PRO Name | 2-phosphoxylose phosphatase 1 (human) |
Definition | A 2-phosphoxylose phosphatase 1 that is encoded in the genome of human. |
Short Label | hPXYLP1 |
Category | organism-gene |
Q8TE99 (PXYLP1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T53 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
Y101 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y104 | Phosphorylation | score1 | PhosphoSitePlus | |||
K110 | Ubiquitination | score1 | PhosphoSitePlus | |||
T117 | Phosphorylation | score1 | PhosphoSitePlus | |||
K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
K207 | Ubiquitination | score1 | PhosphoSitePlus | |||
K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
K267 | Ubiquitination | score1 | PhosphoSitePlus | |||
K287 | Ubiquitination | score1 | PhosphoSitePlus | |||
K325 | Ubiquitination | score1 | PhosphoSitePlus | |||
K444 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T53 | M53 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
T53 | S53 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
Y104 | C104 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
K256 | N256 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |