iPTMnet Report for Q8TE99 (PXYLP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TE99 / PXYP1_HUMAN
Protein Name 2-phosphoxylose phosphatase 1
Gene Name Name: PXYLP1
Synonyms:ACPL2,HEL124;ORFNames:UNQ370/PRO706;
Organism Homo sapiens (Human)

PRO ID PR:Q8TE99
DAG View
PRO Name 2-phosphoxylose phosphatase 1 (human)
Definition A 2-phosphoxylose phosphatase 1 that is encoded in the genome of human.
Short Label hPXYLP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TE99 (PXYLP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T53 O-Glycosylation GlyGen 30459171
Y101 Phosphorylation PhosphoSitePlus
Y104 Phosphorylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
T117 Phosphorylation PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K267 Ubiquitination PhosphoSitePlus
K287 Ubiquitination PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K444 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T53 M53 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T53 S53 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
Y104 C104 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
K256 N256 Biomuta DOID:9256 / colorectal cancer [ cosmic ]