iPTMnet Report for Q8TE73 (DNAH5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TE73 / DYH5_HUMAN
Protein Name Dynein axonemal heavy chain 5
Gene Name Name: DNAH5
Synonyms:DNAHC5,HL1,KIAA1603;
Organism Homo sapiens (Human)

PRO ID PR:Q8TE73
DAG View
PRO Name dynein axonemal heavy chain 5 (human)
Definition A dynein axonemal heavy chain 5 that is encoded in the genome of human.
Short Label hDNAH5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TE73 (DNAH5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K23 Ubiquitination PhosphoSitePlus
Y83 Phosphorylation PhosphoSitePlus
Y84 Phosphorylation PhosphoSitePlus
T92 Phosphorylation PhosphoSitePlus
K310 Acetylation PhosphoSitePlus
T401 Phosphorylation PhosphoSitePlus
S406 Phosphorylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
Y596 Phosphorylation PhosphoSitePlus
Y759 Phosphorylation PhosphoSitePlus
T939 Phosphorylation PhosphoSitePlus
T977 Phosphorylation PhosphoSitePlus
K1058 Ubiquitination PhosphoSitePlus
T1125 Phosphorylation PhosphoSitePlus
S1129 Phosphorylation PhosphoSitePlus
R1226 Methylation PhosphoSitePlus
S1537 Phosphorylation HPRD   PhosphoSitePlus 19664994
Y1600 Phosphorylation PhosphoSitePlus
S2043 Phosphorylation IEDB 35494241
Y2138 Phosphorylation PhosphoSitePlus
Y2549 Phosphorylation PhosphoSitePlus
Y2551 Phosphorylation PhosphoSitePlus
Y2559 Phosphorylation PhosphoSitePlus
S2964 Phosphorylation PhosphoSitePlus
Y3178 Phosphorylation PhosphoSitePlus
Y3185 Phosphorylation PhosphoSitePlus
K3485 Acetylation PhosphoSitePlus
T3488 Phosphorylation PhosphoSitePlus
S3494 Phosphorylation PhosphoSitePlus
K3500 Acetylation PhosphoSitePlus
S3642 Phosphorylation PhosphoSitePlus
T3744 Phosphorylation PhosphoSitePlus
T3751 Phosphorylation PhosphoSitePlus
T3942 Phosphorylation PhosphoSitePlus
S3950 Phosphorylation PhosphoSitePlus
S3963 Phosphorylation PhosphoSitePlus
T4070 Phosphorylation PhosphoSitePlus
Y4072 Phosphorylation PhosphoSitePlus
S4074 Phosphorylation PhosphoSitePlus
Y4244 Phosphorylation PhosphoSitePlus
Y4251 Phosphorylation PhosphoSitePlus
T4256 Phosphorylation PhosphoSitePlus
Y4259 Phosphorylation PhosphoSitePlus
S4345 Phosphorylation HPRD   PhosphoSitePlus 17924679
T4351 Phosphorylation HPRD   PhosphoSitePlus 17924679
S4425 Phosphorylation PhosphoSitePlus
S4555 Phosphorylation PhosphoSitePlus
K4588 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y83 H83 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T939 M939 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
T977 I977 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T1125 K1125 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1129 F1129 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1129 Y1129 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
R1226 Q1226 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R1226 L1226 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R1226 W1226 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S2043 L2043 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S2964 N2964 Biomuta [ cosmic ]
S2964 G2964 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y3185 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S3963 L3963 Biomuta [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1115 / sarcoma [ icgc ] DOID:4159 / skin cancer [ cosmic, icgc ]
S3963 W3963 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y4072 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S4074 F4074 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y4244 C4244 Biomuta DOID:4159 / skin cancer [ cosmic ]
S4345 Y4345 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S4345 C4345 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S4425 R4425 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S4555 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S4555 L4555 Biomuta DOID:4159 / skin cancer [ cosmic ]
K4588 R4588 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]