iPTMnet Report for Q8TDR2 (STK35)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TDR2 / STK35_HUMAN
Protein Name Serine/threonine-protein kinase 35
Gene Name Name: STK35
Synonyms:CLIK1,PDIK1,STK35L1;
Organism Homo sapiens (Human)

PRO ID PR:Q8TDR2
DAG View
PRO Name serine/threonine-protein kinase 35 (human)
Definition A serine/threonine-protein kinase 35 that is encoded in the genome of human.
Short Label hSTK35
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TDR2 (STK35) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
T145 Phosphorylation HPRD 18691976
Y202 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
Y213 Phosphorylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K378 Ubiquitination PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
S418 Phosphorylation PhosphoSitePlus
T452 O-Glycosylation GlyGen 30620550
T465 Phosphorylation PhosphoSitePlus
K468 Ubiquitination PhosphoSitePlus
K485 Ubiquitination PhosphoSitePlus
T496 Phosphorylation PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus
S499 Phosphorylation PhosphoSitePlus
K503 Ubiquitination PhosphoSitePlus
K507 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S385 N385 Biomuta [ cosmic ]
K386 N386 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S414 L414 Biomuta DOID:4606 / bile duct cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S418 L418 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K485 N485 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K485 M485 Biomuta DOID:4159 / skin cancer [ cosmic ]
S499 A499 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]