iPTMnet Report for Q8TCB7 (METTL6)
Protein Information
UniProt AC / UniProt ID | Q8TCB7 / METL6_HUMAN |
Protein Name | tRNA N(3)-methylcytidine methyltransferase METTL6 |
Gene Name | Name: METTL6 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TCB7 |
PRO Name | tRNA N(3)-methylcytidine methyltransferase METTL6 (human) |
Definition | A tRNA N(3)-methylcytidine methyltransferase METTL6 that is encoded in the genome of human. |
Short Label | hMETTL6 |
Category | organism-gene |
Q8TCB7 (METTL6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
K120 | Ubiquitination | score1 | PhosphoSitePlus | |||
S204 | Phosphorylation | score1 | PhosphoSitePlus | |||
S274 | Phosphorylation | score1 | PhosphoSitePlus | |||
S284 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S204 | R204 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] |