iPTMnet Report for Q8TC92 (ENOX1)
Protein Information
UniProt AC / UniProt ID | Q8TC92 / ENOX1_HUMAN |
Protein Name | Ecto-NOX disulfide-thiol exchanger 1 |
Gene Name | Name: ENOX1 ORFNames:PIG38; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TC92 |
PRO Name | ecto-NOX disulfide-thiol exchanger 1 (human) |
Definition | An ecto-NOX disulfide-thiol exchanger 1 that is encoded in the genome of human. |
Short Label | hENOX1 |
Category | organism-gene |
Q8TC92 (ENOX1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S254 | Phosphorylation | score1 | PhosphoSitePlus | |||
K272 | Ubiquitination | score1 | PhosphoSitePlus | |||
S299 | Phosphorylation | score1 | PhosphoSitePlus | |||
S312 | O-Glycosylation | score1 | GlyGen | 36240223 | ||
S403 | Phosphorylation | score1 | PhosphoSitePlus | |||
S410 | Phosphorylation | score1 | PhosphoSitePlus | |||
T412 | Phosphorylation | score1 | PhosphoSitePlus | |||
S435 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y443 | Phosphorylation | score1 | PhosphoSitePlus | |||
T465 | Phosphorylation | score1 | PhosphoSitePlus | |||
T476 | Phosphorylation | score1 | PhosphoSitePlus | |||
K502 | Ubiquitination | score1 | PhosphoSitePlus | |||
T622 | Phosphorylation | score1 | PhosphoSitePlus | |||
T627 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S254 | P254 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
S299 | Y299 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S299 | F299 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y443 | C443 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
T465 | N465 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T622 | M622 | Biomuta | [ cosmic ] DOID:4159 / skin cancer [ cosmic ] | |
T627 | M627 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] |