Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TC41 / RN217_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF217
Gene Name Name: RNF217
Synonyms:C6orf172,IBRDC1,OSTL;
Organism Homo sapiens (Human)

PRO ID PR:Q8TC41
DAG View
PRO Name E3 ubiquitin-protein ligase RNF217 (human)
Definition An E3 ubiquitin-protein ligase RNF217 that is encoded in the genome of human.
Short Label hRNF217
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TC41 (RNF217) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S156 Phosphorylation PhosphoSitePlus
T363 Phosphorylation PhosphoSitePlus
S365 Phosphorylation PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
Y456 Phosphorylation PhosphoSitePlus
K475 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K475 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K475 N475 Biomuta DOID:4159 / skin cancer [ cosmic ]