iPTMnet Report for Q8TC27 (ADAM32)
Protein Information
UniProt AC / UniProt ID | Q8TC27 / ADA32_HUMAN |
Protein Name | Disintegrin and metalloproteinase domain-containing protein 32 precursor |
Gene Name | Name: ADAM32 ORFNames:UNQ5982/PRO21340; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TC27 |
PRO Name | disintegrin and metalloproteinase domain-containing protein 32 (human) |
Definition | A disintegrin and metalloproteinase domain-containing protein 32 that is encoded in the genome of human. |
Short Label | hADAM32 |
Category | organism-gene |
Q8TC27 (ADAM32) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S17 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 17081983, 20068231 | ||
T210 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y275 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y282 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y285 | Phosphorylation | score1 | PhosphoSitePlus | |||
S300 | Phosphorylation | score1 | PhosphoSitePlus | |||
R551 | Methylation | score1 | PhosphoSitePlus | |||
S733 | Phosphorylation | score1 | PhosphoSitePlus | |||
S753 | Phosphorylation | score1 | PhosphoSitePlus | |||
S754 | Phosphorylation | score1 | PhosphoSitePlus | |||
T771 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S17 | P17 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
Y282 | C282 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |