iPTMnet Report for Q8TB36 (GDAP1)
Protein Information
UniProt AC / UniProt ID | Q8TB36 / GDAP1_HUMAN |
Protein Name | Ganglioside-induced differentiation-associated protein 1 |
Gene Name | Name: GDAP1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8TB36 |
PRO Name | ganglioside-induced differentiation-associated protein 1 (human) |
Definition | A ganglioside-induced differentiation-associated protein 1 that is encoded in the genome of human. |
Short Label | hGDAP1 |
Category | organism-gene |
Q8TB36 (GDAP1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S11 | Phosphorylation | score1 | PhosphoSitePlus | |||
K47 | Ubiquitination | score1 | PhosphoSitePlus | |||
K50 | Ubiquitination | score1 | UniProt | 25621951 | ||
K113 | Ubiquitination | score1 | PhosphoSitePlus | |||
S162 | Phosphorylation | score1 | PhosphoSitePlus | |||
K172 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
K173 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
K188 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
K190 | Ubiquitination | score1 | UniProt | 25621951 | ||
K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
K203 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K203 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
Y204 | Phosphorylation | score1 | PhosphoSitePlus | |||
K206 | Ubiquitination | score1 | UniProt | 25621951 | ||
K207 | Ubiquitination | score2 | PhosphoSitePlus UniProt | 25621951 | ||
K214 | Ubiquitination | score1 | UniProt | 25621951 | ||
K259 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K50 | T50 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K206 | R206 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K259 | * | Biomuta | DOID:1612 / breast cancer [ cosmic ] |