iPTMnet Report for Q8TAD8 (SNIP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8TAD8 / SNIP1_HUMAN
Protein Name Smad nuclear-interacting protein 1
Gene Name Name: SNIP1
Organism Homo sapiens (Human)

PRO ID PR:Q8TAD8
DAG View
PRO Name smad nuclear-interacting protein 1 (human)
Definition A smad nuclear-interacting protein 1 that is encoded in the genome of human.
Short Label hSNIP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8TAD8 (SNIP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Sumoylation PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus
K30 Sumoylation PhosphoSitePlus
S35 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17322306, 21406692, 23186163, ...18212344, 18220336, 18767875, 19007248, 18452278, 19651622, 18669648, 20068231, 17081983
S49 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 17081983, ...20068231
S52 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 23186163, 17322306, ...18669648, 24275569, 19690332, 20068231
S54 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18767875, 19651622, 18669648, 24275569, 20068231
T57 Phosphorylation PhosphoSitePlus   UniProt 23186163
S58 Phosphorylation PhosphoSitePlus   UniProt 23186163
S74 Phosphorylation HPRD   PhosphoSitePlus 19651622, 20068231
S76 Phosphorylation HPRD   PhosphoSitePlus 19651622, 20068231
K79 Acetylation PhosphoSitePlus
K80 Acetylation PhosphoSitePlus
S89 Phosphorylation HPRD 17081983
S91 Phosphorylation HPRD 17081983
S99 Phosphorylation HPRD   PhosphoSitePlus 20068231
T104 Phosphorylation HPRD   PhosphoSitePlus 20068231
K108 Sumoylation PhosphoSitePlus
S128 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
T152 Phosphorylation HPRD   PhosphoSitePlus 20068231
S153 Phosphorylation HPRD   PhosphoSitePlus 19651622, 17081983, 19664995
S159 Phosphorylation HPRD   PhosphoSitePlus 19651622, 17081983
T169 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
S200 Phosphorylation PhosphoSitePlus
S202 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163, 18452278
K223 Ubiquitination PhosphoSitePlus
T236 Phosphorylation HPRD 20068231
K301 Ubiquitination PhosphoSitePlus
Y308 Phosphorylation PhosphoSitePlus
Y313 Phosphorylation PhosphoSitePlus
T314 Phosphorylation PhosphoSitePlus
K325 Ubiquitination PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
Y349 Phosphorylation PhosphoSitePlus
Y350 Phosphorylation PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
S394 Phosphorylation HPRD   PhosphoSitePlus   UniProt 17081983, 20068231, 18452278
S396 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S91 Y91 Biomuta DOID:363 / uterine cancer [ icgc ]
S91 F91 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K108 N108 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S147 A147 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
T169 I169 Biomuta DOID:4159 / skin cancer [ cosmic ]