iPTMnet Report for Q8NG68 (TTL)
Protein Information
UniProt AC / UniProt ID | Q8NG68 / TTL_HUMAN |
Protein Name | Tubulin--tyrosine ligase |
Gene Name | Name: TTL |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8NG68 |
PRO Name | tubulin--tyrosine ligase (human) |
Definition | A tubulin--tyrosine ligase that is encoded in the genome of human. |
Short Label | hTTL |
Category | organism-gene |
Q8NG68 (TTL) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S18 | Phosphorylation | score1 | PhosphoSitePlus | |||
T24 | Phosphorylation | score1 | PhosphoSitePlus | |||
K138 | Acetylation | score1 | PhosphoSitePlus | |||
K150 | Acetylation | score1 | PhosphoSitePlus | |||
K150 | Ubiquitination | score1 | PhosphoSitePlus | |||
S152 | Phosphorylation | score0 | RLIMS-P | 23358242 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K138 | N138 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S152 | L152 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |