Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NG66 / NEK11_HUMAN
Protein Name Serine/threonine-protein kinase Nek11
Gene Name Name: NEK11
Organism Homo sapiens (Human)

PRO ID PR:Q8NG66
DAG View
PRO Name serine/threonine-protein kinase Nek11 (human)
Definition A serine/threonine-protein kinase Nek11 that is encoded in the genome of human.
Short Label hNEK11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NG66 (NEK11) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y29 Phosphorylation IEDB 35494241
Y44 Phosphorylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
S84 Phosphorylation IEDB 35494241
K85 Ubiquitination PhosphoSitePlus
S273 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   Signor   UniProt 20090422, 19734889
S273 Phosphorylation O14757 (CHEK1) neXtProt   PhosphoSitePlus   Signor 19734889
K312 Acetylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T585 Phosphorylation PhosphoSitePlus


Q8NG66 (NEK11) as PTM Enzyme



Substrate Site Score Source PMID
P30304 (CDC25A) S79 neXtProt   PhosphoSitePlus 19734889
P30304 (CDC25A) S82 neXtProt   PhosphoSitePlus   Signor 19734889
P30304 (CDC25A) S88 neXtProt   PhosphoSitePlus   Signor 19734889
P54132 (BLM) S338 PhosphoSitePlus 24239288


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S273 L273 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S387 C387 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]