iPTMnet Report for Q8NG08 (HELB)
Protein Information
UniProt AC / UniProt ID | Q8NG08 / HELB_HUMAN |
Protein Name | DNA helicase B |
Gene Name | Name: HELB |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8NG08 |
PRO Name | DNA helicase B (human) |
Definition | A DNA helicase B that is encoded in the genome of human. |
Short Label | hHELB |
Category | organism-gene |
Q8NG08 (HELB) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S64 | Phosphorylation | score1 | PhosphoSitePlus | |||
K75 | Ubiquitination | score1 | PhosphoSitePlus | |||
K143 | Ubiquitination | score1 | PhosphoSitePlus | |||
T146 | Phosphorylation | score1 | PhosphoSitePlus | |||
S152 | Phosphorylation | score1 | PhosphoSitePlus | |||
K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
S235 | Phosphorylation | score1 | PhosphoSitePlus | |||
K254 | Ubiquitination | score1 | PhosphoSitePlus | |||
K336 | Ubiquitination | score1 | PhosphoSitePlus | |||
K393 | Ubiquitination | score1 | PhosphoSitePlus | |||
S467 | Phosphorylation | score1 | PhosphoSitePlus | |||
S486 | Phosphorylation | score1 | PhosphoSitePlus | |||
T640 | Phosphorylation | score1 | PhosphoSitePlus | |||
K642 | Ubiquitination | score1 | PhosphoSitePlus | |||
K651 | Ubiquitination | score1 | PhosphoSitePlus | |||
S658 | Phosphorylation | score1 | PhosphoSitePlus | |||
S708 | Phosphorylation | score1 | PhosphoSitePlus | |||
S709 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y721 | Phosphorylation | score1 | PhosphoSitePlus | |||
K737 | Ubiquitination | score1 | PhosphoSitePlus | |||
K779 | Ubiquitination | score1 | PhosphoSitePlus | |||
S828 | Phosphorylation | score1 | PhosphoSitePlus | |||
S967 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 23186163, 15146062 | ||
S979 | Phosphorylation | score1 | PhosphoSitePlus | |||
T980 | Phosphorylation | score1 | PhosphoSitePlus | |||
S982 | Phosphorylation | score1 | PhosphoSitePlus | |||
S984 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1020 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1021 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1027 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
T1040 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1048 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1058 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S1062 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1063 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K143 | T143 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S235 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K336 | T336 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S467 | C467 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K651 | E651 | Biomuta | DOID:3571 / liver cancer [ icgc ] | |
S709 | Y709 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K737 | N737 | Biomuta | [ cosmic ] | |
K779 | E779 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
S967 | F967 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S979 | N979 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S979 | I979 | Biomuta | DOID:1324 / lung cancer [ tcga ] | |
T980 | I980 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
S1021 | L1021 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |