iPTMnet Report for Q8NG06 (TRIM58)
Protein Information
UniProt AC / UniProt ID | Q8NG06 / TRI58_HUMAN |
Protein Name | E3 ubiquitin-protein ligase TRIM58 |
Gene Name | Name: TRIM58 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8NG06 |
PRO Name | E3 ubiquitin-protein ligase TRIM58 (human) |
Definition | An E3 ubiquitin-protein ligase TRIM58 that is encoded in the genome of human. |
Short Label | hTRIM58 |
Category | organism-gene |
Q8NG06 (TRIM58) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y55 | Phosphorylation | score1 | PhosphoSitePlus | |||
T159 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y392 | Phosphorylation | score1 | PhosphoSitePlus | |||
S397 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y55 | H55 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
Y392 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S397 | Y397 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |