iPTMnet Report for Q8NFQ8 (TOR1AIP2)
Protein Information
UniProt AC / UniProt ID | Q8NFQ8 / TOIP2_HUMAN |
Protein Name | Torsin-1A-interacting protein 2 |
Gene Name | Name: TOR1AIP2 Synonyms:IFRG15,LULL1; |
Organism | Homo sapiens (Human) |
Q8NFQ8 (TOR1AIP2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 21406692 | ||
S4 | O-Glycosylation | score1 | GlyGen | 33465208, 35254053 | ||
S4 | Phosphorylation | score1 | PhosphoSitePlus | |||
R7 | Methylation | score1 | PhosphoSitePlus | |||
S13 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
T58 | Phosphorylation | score1 | PhosphoSitePlus | |||
S70 | Phosphorylation | score1 | PhosphoSitePlus | |||
S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
T86 | Phosphorylation | score1 | PhosphoSitePlus | |||
S93 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S118 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S120 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S150 | Phosphorylation | score1 | PhosphoSitePlus | |||
T155 | Phosphorylation | score1 | PhosphoSitePlus | |||
S158 | Phosphorylation | score1 | PhosphoSitePlus | |||
S163 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
S167 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
S168 | Phosphorylation | score1 | PhosphoSitePlus | |||
T176 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
S188 | Phosphorylation | score1 | PhosphoSitePlus | |||
T193 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
K200 | Ubiquitination | score1 | PhosphoSitePlus | |||
N286 | N-Glycosylation | score1 | GlyGen | 23090970, 29741879, 24190977 | ||
S288 | O-Glycosylation | score1 | GlyGen | 33465208, 35254053 | ||
N289 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
K309 | Ubiquitination | score1 | PhosphoSitePlus | |||
K324 | Ubiquitination | score1 | PhosphoSitePlus | |||
S326 | Phosphorylation | score1 | PhosphoSitePlus | |||
K425 | Ubiquitination | score1 | PhosphoSitePlus | |||
N428 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
T433 | Phosphorylation | score1 | PhosphoSitePlus | |||
S440 | Phosphorylation | score1 | PhosphoSitePlus | |||
K442 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S118 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
S120 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
S122 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
S150 | Phosphorylation | score0 | HPRD | 18077418 | ||
S158 | Phosphorylation | score0 | HPRD | 18691976, 18077418 | ||
S163 | Phosphorylation | score0 | HPRD | 18669648 | ||
S167 | Phosphorylation | score0 | HPRD | 18669648 | ||
S326 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S70 | L70 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K195 | T195 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
K195 | * | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
S288 | F288 | Biomuta | DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
K425 | M425 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] |