iPTMnet Report Q8NFF5 FLAD1

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q8NFF5 / FAD1_HUMAN
Protein Name	FAD synthase precursor
Gene Name	Name: FLAD1 ORFNames:PP591;
Organism	Homo sapiens (Human)

PRO ID	PR:Q8NFF5 DAG View
PRO Name	FAD synthase (human)
Definition	An FAD synthase that is encoded in the genome of human.
Short Label	hFLAD1
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q8NFF5 (FLAD1) as Substrate

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S106	Phosphorylation		score2	IEDB phospho.ELM PhosphoSitePlus UniProt	27920218, 18669648, 16964243, ...18691976
	C136	Methylation		score1	IEDB	31844290
	S141	Phosphorylation		score1	PhosphoSitePlus
	K210	Ubiquitination		score1	PhosphoSitePlus
	K219	Ubiquitination		score1	PhosphoSitePlus
	K378	Ubiquitination		score1	PhosphoSitePlus
	S440	Phosphorylation		score1	PhosphoSitePlus
	T553	Phosphorylation		score1	PhosphoSitePlus
	S563	Phosphorylation		score2	PhosphoSitePlus UniProt	18691976, 23186163, 19369195
	Y570	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S106	Phosphorylation		score0	HPRD	18691976, 18669648, 16964243, ...20068231
	S141	Phosphorylation		score0	HPRD	20068231
	S563	Phosphorylation		score0	HPRD	18691976

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S9	Phosphorylation		score0	HPRD	18691976, 18669648, 16964243, ...20068231
	S44	Phosphorylation		score0	HPRD	20068231
	S466	Phosphorylation		score0	HPRD	18691976

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
K378	E378	Biomuta		DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S440	F440	Biomuta		DOID:4159 / skin cancer [ cosmic ]
T553	I553	Biomuta		DOID:4159 / skin cancer [ cosmic ]