Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NFD2 / ANKK1_HUMAN
Protein Name Ankyrin repeat and protein kinase domain-containing protein 1
Gene Name Name: ANKK1
Synonyms:PKK2,SGK288;
Organism Homo sapiens (Human)

PRO ID PR:Q8NFD2
DAG View
PRO Name ankyrin repeat and protein kinase domain-containing protein 1 (human)
Definition An ankyrin repeat and protein kinase domain-containing protein 1 that is encoded in the genome of human.
Short Label hANKK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NFD2 (ANKK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T6 Phosphorylation PhosphoSitePlus
Y190 Phosphorylation PhosphoSitePlus
R237 Methylation PhosphoSitePlus
Y336 Phosphorylation PhosphoSitePlus
K577 Acetylation PhosphoSitePlus
T590 Phosphorylation PhosphoSitePlus
T694 Phosphorylation PhosphoSitePlus
K702 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R237 Q237 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y336 H336 Biomuta DOID:1612 / breast cancer [ cosmic ]
T590 A590 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T694 K694 Biomuta DOID:1612 / breast cancer [ cosmic ]