iPTMnet Report for Q8NF64 (ZMIZ2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NF64 / ZMIZ2_HUMAN
Protein Name Zinc finger MIZ domain-containing protein 2
Gene Name Name: ZMIZ2
Synonyms:KIAA1886,ZIMP7;ORFNames:HRIHFB2007;
Organism Homo sapiens (Human)

PRO ID PR:Q8NF64
DAG View
PRO Name zinc finger MIZ domain-containing protein 2 (human)
Definition A zinc finger MIZ domain-containing protein 2 that is encoded in the genome of human.
Short Label hZMIZ2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NF64 (ZMIZ2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K101 Sumoylation PhosphoSitePlus
Y109 Phosphorylation PhosphoSitePlus
R111 Methylation PhosphoSitePlus
T145 O-Glycosylation GlyGen 34019948, 35254053
T159 O-Glycosylation GlyGen 34019948, 35254053
S190 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
R245 Methylation PhosphoSitePlus   UniProt 24129315
R262 Methylation PhosphoSitePlus   UniProt 24129315
K266 Methylation PhosphoSitePlus
R309 Methylation IEDB 27503676
Y365 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
T375 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
S382 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
K402 Sumoylation PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
T505 Phosphorylation PhosphoSitePlus
S506 Phosphorylation PhosphoSitePlus
K555 Sumoylation PhosphoSitePlus
C564 Methylation IEDB 31844290
T580 Phosphorylation PhosphoSitePlus
C632 Methylation IEDB 31844290
K701 Acetylation PhosphoSitePlus
S707 Phosphorylation IEDB 32387766


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R111 C111 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T145 M145 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R245 H245 Biomuta DOID:1319 / brain cancer [ icgc ]
R245 C245 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S368 F368 Biomuta DOID:4159 / skin cancer [ cosmic ]
S381 I381 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S382 G382 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S388 L388 Biomuta DOID:3571 / liver cancer [ cosmic ]
T505 P505 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]