iPTMnet Report for Q8NEZ5 (FBXO22)
Protein Information
UniProt AC / UniProt ID | Q8NEZ5 / FBX22_HUMAN |
Protein Name | F-box only protein 22 |
Gene Name | Name: FBXO22 Synonyms:FBX22; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8NEZ5 |
PRO Name | F-box only protein 22 (human) |
Definition | An F-box only protein 22 that is encoded in the genome of human. |
Short Label | hFBXO22 |
Category | organism-gene |
Q8NEZ5 (FBXO22) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 19413330, 22814378, 22223895 | ||
K40 | Acetylation | score1 | PhosphoSitePlus | |||
K40 | Ubiquitination | score1 | PhosphoSitePlus | |||
C83 | Methylation | score1 | IEDB | 31844290 | ||
Y104 | Phosphorylation | score1 | PhosphoSitePlus | |||
S128 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K137 | Ubiquitination | score1 | PhosphoSitePlus | |||
S160 | Phosphorylation | score1 | PhosphoSitePlus | |||
S162 | Phosphorylation | score1 | PhosphoSitePlus | |||
K194 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K194 | Ubiquitination | score1 | PhosphoSitePlus | |||
K300 | Ubiquitination | score1 | PhosphoSitePlus | |||
K337 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C83 | Y83 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:363 / uterine cancer [ icgc ] | |
Y104 | C104 | Biomuta | DOID:363 / uterine cancer [ icgc ] |