iPTMnet Report for Q8NEG7 (DENND6B)
Protein Information
| UniProt AC / UniProt ID | Q8NEG7 / DEN6B_HUMAN |
| Protein Name | Protein DENND6B |
| Gene Name | Name: DENND6B Synonyms:FAM116B; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8NEG7 |
| PRO Name | protein DENND6B (human) |
| Definition | A protein FAM116B that is encoded in the genome of human. |
| Short Label | hDENND6B |
| Category | organism-gene |
DAG ViewQ8NEG7 (DENND6B) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y115 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S117 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T320 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
| T321 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
| K378 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S409 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S413 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C475 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K378 | N378 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S409 | L409 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| C475 | R475 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
