iPTMnet Report for Q8NE71 (ABCF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NE71 / ABCF1_HUMAN
Protein Name ATP-binding cassette sub-family F member 1
Gene Name Name: ABCF1
Synonyms:ABC50;
Organism Homo sapiens (Human)

PRO ID PR:Q8NE71
DAG View
PRO Name ATP-binding cassette sub-family F member 1 (human)
Definition An ATP-binding cassette sub-family F member 1 that is encoded in the genome of human.
Short Label hABCF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NE71 (ABCF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Ubiquitination PhosphoSitePlus
S20 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T21 Phosphorylation PhosphoSitePlus
S22 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S24 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K26 Ubiquitination PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K50 Ubiquitination PhosphoSitePlus
S105 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16083285, 23186163, 17081983, ...18669648, 24275569, 20068231
T108 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 16083285, 23186163, ...17081983, 15302935, 18669648, 24275569, 19690332, 20068231
S109 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor   UniProt 21406692, 16083285, 23186163, ...17081983, 15302935, 18669648, 17894550, 18088087, 19690332, 20068231
S109 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 17894550
S140 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor   UniProt 21406692, 23186163, 17081983, ...18669648, 17894550, 17287340, 19690332, 20068231
S140 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 17894550
K163 Acetylation PhosphoSitePlus
K163 Methylation PhosphoSitePlus
S166 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692
K174 Methylation PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
K176 Methylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
S228 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340, 16964243, ...15302935, 18318008, 18669648, 23186163, 19690332, 20068231, 17081983
S244 Phosphorylation PhosphoSitePlus
Y250 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
Y267 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus
K275 Methylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
S287 Phosphorylation PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
K308 Ubiquitination PhosphoSitePlus
Y332 Phosphorylation PhosphoSitePlus
T343 Phosphorylation PhosphoSitePlus
T344 Phosphorylation PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
K389 Ubiquitination PhosphoSitePlus
T407 Phosphorylation PhosphoSitePlus
K414 Ubiquitination PhosphoSitePlus
Y416 Phosphorylation PhosphoSitePlus
T422 Phosphorylation PhosphoSitePlus
K430 Ubiquitination PhosphoSitePlus
K451 Ubiquitination PhosphoSitePlus
K537 Methylation PhosphoSitePlus
K549 Ubiquitination PhosphoSitePlus
Y551 Phosphorylation PhosphoSitePlus
K573 Ubiquitination PhosphoSitePlus
K576 Ubiquitination PhosphoSitePlus
T580 Phosphorylation PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus
K589 Ubiquitination PhosphoSitePlus
S595 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163
K603 Ubiquitination PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus
S652 Phosphorylation PhosphoSitePlus
S665 Phosphorylation PhosphoSitePlus
T666 Phosphorylation PhosphoSitePlus
T672 Phosphorylation PhosphoSitePlus
T676 Phosphorylation PhosphoSitePlus
T678 Phosphorylation PhosphoSitePlus
K689 Ubiquitination PhosphoSitePlus
Y710 Phosphorylation PhosphoSitePlus
C741 Methylation IEDB 31844290
K742 Acetylation PhosphoSitePlus
K748 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation HPRD 18669648, 19664995
T21 Phosphorylation HPRD 20068231
S22 Phosphorylation HPRD 19413330, 17081983, 19664994, ...18452278, 19651622, 18669648, 19415658, 20068231
S24 Phosphorylation HPRD 19413330, 18669648, 19664995, ...20068231, 18452278
S105 Phosphorylation HPRD 20230923, 18452278, 19651622, ...18669648, 18707149, 20166139, 15345747, 20068231
T108 Phosphorylation HPRD 19413330, 20230923, 19562805, ...20058876, 15302935, 18452278, 19651622, 18669648, 18707149, 20166139, 19415658, 20068231
S109 Phosphorylation HPRD 19413330, 18578522, 18088087, ...20230923, 18767875, 15302935, 18452278, 19651622, 18669648, 20058876, 18707149, 20166139, 15345747, 19415658, 20068231
S140 Phosphorylation HPRD 19413330, 17287340, 17081983, ...18767875, 20058876, 18452278, 19651622, 18669648, 20068231
S166 Phosphorylation HPRD 18669648
S228 Phosphorylation HPRD 17287340, 16964243, 18452278, ...19651622, 18669648, 20166139, 19415658, 20068231, 17081983
S244 Phosphorylation HPRD 19651622
Y267 Phosphorylation HPRD 19664994
T422 Phosphorylation HPRD 20068231
S595 Phosphorylation HPRD 19651622, 17525332, 18452278
T678 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S20 Phosphorylation HPRD 18669648, 19664995
T21 Phosphorylation HPRD 20068231
S22 Phosphorylation HPRD 19413330, 17081983, 19664994, ...18452278, 19651622, 18669648, 19415658, 20068231
S24 Phosphorylation HPRD 19413330, 18669648, 19664995, ...20068231, 18452278
S105 Phosphorylation HPRD 20230923, 18452278, 19651622, ...18669648, 18707149, 20166139, 15345747, 20068231
T108 Phosphorylation HPRD 19413330, 17322306, 20230923, ...19562805, 20058876, 18452278, 19651622, 18669648, 18707149, 20166139, 19415658, 20068231
S109 Phosphorylation HPRD 19413330, 17322306, 18578522, ...18088087, 20230923, 18767875, 20058876, 18452278, 19651622, 18669648, 18707149, 20166139, 19415658, 20068231
S140 Phosphorylation HPRD 19413330, 17287340, 17081983, ...18767875, 20058876, 18452278, 19651622, 18669648, 20068231
S166 Phosphorylation HPRD 18669648
T384 Phosphorylation HPRD 20068231
S557 Phosphorylation HPRD 19651622, 17525332, 18452278
T640 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S20 N20 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S22 C22 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S140 I140 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S140 T140 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]