iPTMnet Report for Q8NDI1 (EHBP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NDI1 / EHBP1_HUMAN
Protein Name EH domain-binding protein 1
Gene Name Name: EHBP1
Synonyms:KIAA0903,NACSIN;
Organism Homo sapiens (Human)

PRO ID PR:Q8NDI1
DAG View
PRO Name EH domain-binding protein 1 (human)
Definition An EH domain-binding protein 1 that is encoded in the genome of human.
Short Label hEHBP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NDI1 (EHBP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K33 Acetylation PhosphoSitePlus
K34 Acetylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
T165 Phosphorylation PhosphoSitePlus
S171 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18669648, ...19690332, 20068231
S174 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231, ...19690332
S177 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K206 Ubiquitination PhosphoSitePlus
T291 Phosphorylation PhosphoSitePlus
T293 Phosphorylation PhosphoSitePlus
T299 Phosphorylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y304 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y319 Phosphorylation PhosphoSitePlus
T331 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S335 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
Y355 Phosphorylation PhosphoSitePlus
S358 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
T378 Phosphorylation PhosphoSitePlus
T393 O-Glycosylation GlyGen 30379171
S408 Phosphorylation PhosphoSitePlus   UniProt 23186163
S420 Phosphorylation PhosphoSitePlus
S426 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 18220336
T427 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S428 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 18669648, 23186163, ...18220336
S432 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 24275569
S436 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...18220336, 15302935, 18669648, 24275569, 19690332, 20068231
S577 Phosphorylation PhosphoSitePlus
S578 Phosphorylation PhosphoSitePlus
Y585 Phosphorylation PhosphoSitePlus
S589 Phosphorylation PhosphoSitePlus
K592 Ubiquitination PhosphoSitePlus
T647 Phosphorylation PhosphoSitePlus
S649 Phosphorylation PhosphoSitePlus
T663 Phosphorylation PhosphoSitePlus
S666 Phosphorylation PhosphoSitePlus
T694 Phosphorylation PhosphoSitePlus   UniProt 23186163
S698 Phosphorylation PhosphoSitePlus
Y701 Phosphorylation PhosphoSitePlus
S710 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T718 Phosphorylation PhosphoSitePlus
S730 Phosphorylation PhosphoSitePlus
S742 Phosphorylation PhosphoSitePlus
S747 Phosphorylation PhosphoSitePlus
S751 Phosphorylation PhosphoSitePlus
T756 Phosphorylation PhosphoSitePlus
S759 Phosphorylation PhosphoSitePlus
K763 Ubiquitination PhosphoSitePlus
Y766 Phosphorylation PhosphoSitePlus
S767 Phosphorylation PhosphoSitePlus
Y768 Phosphorylation PhosphoSitePlus
S769 Phosphorylation PhosphoSitePlus
S781 Phosphorylation PhosphoSitePlus   UniProt 23186163
S787 Phosphorylation PhosphoSitePlus
S812 Phosphorylation PhosphoSitePlus
T846 Phosphorylation PhosphoSitePlus
C849 Methylation IEDB 31844290
S854 Phosphorylation PhosphoSitePlus   UniProt 24275569
S887 Phosphorylation PhosphoSitePlus
Y888 Phosphorylation PhosphoSitePlus
S964 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S967 Phosphorylation PhosphoSitePlus
T974 Phosphorylation PhosphoSitePlus
S976 Phosphorylation PhosphoSitePlus
S977 Phosphorylation PhosphoSitePlus
T1011 Phosphorylation PhosphoSitePlus
S1019 Phosphorylation PhosphoSitePlus
Y1023 Phosphorylation PhosphoSitePlus
S1035 Phosphorylation PhosphoSitePlus
T1040 Phosphorylation PhosphoSitePlus
T1051 Phosphorylation IEDB 35494241
T1053 Phosphorylation PhosphoSitePlus
S1058 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...24275569
T1070 Phosphorylation PhosphoSitePlus
K1097 Ubiquitination PhosphoSitePlus
Y1101 Phosphorylation PhosphoSitePlus
K1188 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T165 Phosphorylation HPRD 19651622
S171 Phosphorylation HPRD 19651622, 18669648, 20068231
S174 Phosphorylation HPRD 19651622, 18669648, 20068231
S177 Phosphorylation HPRD 19651622, 18669648, 20068231
S302 Phosphorylation HPRD 20068231
T331 Phosphorylation HPRD 18669648
S335 Phosphorylation HPRD 18669648, 20068231
S426 Phosphorylation HPRD 19413330, 19651622, 18669648, ...20068231
T427 Phosphorylation HPRD 19413330, 18669648, 15144186, ...20068231
S428 Phosphorylation HPRD 19413330, 19651622, 18669648, ...20068231
S432 Phosphorylation HPRD 19413330, 19651622, 18669648, ...20068231
S436 Phosphorylation HPRD 19413330, 15144186, 19651622, ...18669648, 20166139, 20068231
S710 Phosphorylation HPRD 18669648
S964 Phosphorylation HPRD 19413330, 18669648, 20068231
T1053 Phosphorylation HPRD 18452278
S1058 Phosphorylation HPRD 19651622, 20166139, 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K34 E34 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K163 N163 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T165 I165 Biomuta DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
S307 N307 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S335 F335 Biomuta [ cosmic ]
S335 Y335 Biomuta DOID:363 / uterine cancer [ icgc ]
S426 F426 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S428 T428 Biomuta DOID:263 / kidney cancer [ cosmic ]
S428 F428 Biomuta [ cosmic ]
S578 F578 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y585 C585 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
K592 N592 Biomuta DOID:1324 / lung cancer [ cosmic ]
S710 A710 Biomuta DOID:3571 / liver cancer [ cosmic ]
T718 A718 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S730 I730 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S730 N730 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S751 F751 Biomuta DOID:1319 / brain cancer [ icgc ]
S759 Y759 Biomuta DOID:363 / uterine cancer [ icgc ]
Y768 C768 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S769 N769 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S781 F781 Biomuta DOID:4159 / skin cancer [ cosmic ]
S787 F787 Biomuta [ cosmic ]
S812 Y812 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T846 P846 Biomuta DOID:1612 / breast cancer [ cosmic ]
C849 F849 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]
Y888 C888 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S967 C967 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S976 I976 Biomuta DOID:1324 / lung cancer [ cosmic ]
S1035 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]