iPTMnet Report for Q8NDH3 (NPEPL1)
Protein Information
UniProt AC / UniProt ID | Q8NDH3 / PEPL1_HUMAN |
Protein Name | Probable aminopeptidase NPEPL1 |
Gene Name | Name: NPEPL1 Synonyms:KIAA1974; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8NDH3 |
PRO Name | probable aminopeptidase NPEPL1 (human) |
Definition | A probable aminopeptidase NPEPL1 that is encoded in the genome of human. |
Short Label | hNPEPL1 |
Category | organism-gene |
Q8NDH3 (NPEPL1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S88 | Phosphorylation | score1 | PhosphoSitePlus | |||
C189 | Methylation | score1 | IEDB | 31844290 | ||
K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
K221 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y229 | Phosphorylation | score1 | PhosphoSitePlus | |||
S270 | Phosphorylation | score1 | PhosphoSitePlus | |||
K272 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y331 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T96 | M96 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
C189 | R189 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
S270 | G270 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
S270 | N270 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] DOID:2174 / ocular cancer [ tcga ] |