iPTMnet Report for Q8ND30 (PPFIBP2)
Protein Information
| UniProt AC / UniProt ID | Q8ND30 / LIPB2_HUMAN |
| Protein Name | Liprin-beta-2 |
| Gene Name | Name: PPFIBP2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q8ND30 |
| PRO Name | liprin-beta-2 (human) |
| Definition | A liprin-beta-2 that is encoded in the genome of human. |
| Short Label | hPPFIBP2 |
| Category | organism-gene |
Q8ND30 (PPFIBP2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S3 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S40 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T179 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S182 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y310 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T327 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S329 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| S363 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
| S385 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S387 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 24275569 | ||
| S393 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S395 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S414 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y422 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T424 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S441 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T444 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S487 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K502 | Acetylation | score1 | PhosphoSitePlus | |||
| T510 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
| S512 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
| Y516 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T533 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S539 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S585 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y663 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T756 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T759 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T771 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S799 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y802 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S819 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y835 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y852 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y855 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S859 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S329 | Phosphorylation | score0 | HPRD | 20166139, 18669648 | ||
| S387 | Phosphorylation | score0 | HPRD | 18669648, 19664994 | ||
| T510 | Phosphorylation | score0 | HPRD | 18669648 | ||
| S512 | Phosphorylation | score0 | HPRD | 18669648 |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K10 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S329 | A329 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S385 | F385 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S387 | T387 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S414 | N414 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| T424 | P424 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| T510 | I510 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
| S799 | L799 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S819 | L819 | Biomuta | DOID:1319 / brain cancer [ cosmic ] |
DAG View