iPTMnet Report for Q8NC44 (RETREG2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NC44 / RETR2_HUMAN
Protein Name Reticulophagy regulator 2
Gene Name Name: RETREG2
Synonyms:C2orf17,FAM134A,MAG2;
Organism Homo sapiens (Human)

PRO ID PR:Q8NC44
DAG View
PRO Name reticulophagy regulator 2 (human)
Definition A reticulophagy regulator 2 that is encoded in the genome of human.
Short Label hRETREG2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NC44 (RETREG2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S138 Phosphorylation PhosphoSitePlus
Y233 Phosphorylation PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
T279 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231
S281 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231
S283 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231
S291 Phosphorylation PhosphoSitePlus   UniProt 24275569
T306 Phosphorylation HPRD 17081983
S308 Phosphorylation HPRD 17081983
S311 Phosphorylation HPRD   PhosphoSitePlus   UniProt 17081983, 24275569
T329 Phosphorylation PhosphoSitePlus
T330 Phosphorylation PhosphoSitePlus
T334 Phosphorylation PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus   UniProt 19690332
S347 Phosphorylation PhosphoSitePlus   UniProt 19690332, 24275569
S379 Phosphorylation PhosphoSitePlus
S385 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17322306, 18578522, 18088087, ...17081983, 18767875, 19007248, 18452278, 19651622, 18669648, 21406692, 24275569, 23186163, 18318008, 19415658, 20068231
S403 Phosphorylation IEDB   PhosphoSitePlus 32387766
S417 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S379 P379 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S385 L385 Biomuta DOID:10534 / stomach cancer [ cosmic ]