iPTMnet Report for Q8NB90 (AFG2A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NB90 / AFG2A_HUMAN
Protein Name ATPase family gene 2 protein homolog A
Gene Name Name: AFG2A
Synonyms:SPAF;
Organism Homo sapiens (Human)

PRO ID PR:Q8NB90
DAG View
PRO Name ribosome biogenesis protein SPATA5 (human)
Definition A ribosome biogenesis protein SPATA5 that is encoded in the genome of human.
Short Label hSPATA5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NB90 (AFG2A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S13 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
S34 Phosphorylation PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
C81 Methylation IEDB 31844290
K110 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
Y180 Phosphorylation PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
T212 Phosphorylation PhosphoSitePlus
T251 Phosphorylation PhosphoSitePlus
Y253 Phosphorylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
T272 Phosphorylation PhosphoSitePlus   UniProt 20068231
S274 Phosphorylation PhosphoSitePlus   UniProt 20068231
S279 Phosphorylation PhosphoSitePlus   UniProt 20068231
T304 Phosphorylation PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K342 Ubiquitination PhosphoSitePlus
K363 Ubiquitination PhosphoSitePlus
K374 Ubiquitination PhosphoSitePlus
K380 Ubiquitination PhosphoSitePlus
Y393 Phosphorylation PhosphoSitePlus
K400 Ubiquitination PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
K461 Ubiquitination PhosphoSitePlus
K471 Acetylation PhosphoSitePlus
K517 Ubiquitination PhosphoSitePlus
K535 Ubiquitination PhosphoSitePlus
K582 Ubiquitination PhosphoSitePlus
K590 Ubiquitination PhosphoSitePlus
K600 Ubiquitination PhosphoSitePlus
K636 Ubiquitination PhosphoSitePlus
K638 Ubiquitination PhosphoSitePlus
K648 Ubiquitination PhosphoSitePlus
K662 Ubiquitination PhosphoSitePlus
K674 Ubiquitination PhosphoSitePlus
K679 Ubiquitination PhosphoSitePlus
K693 Ubiquitination PhosphoSitePlus
K700 Ubiquitination PhosphoSitePlus
T755 Phosphorylation PhosphoSitePlus
T801 Phosphorylation PhosphoSitePlus
T863 Phosphorylation PhosphoSitePlus
S867 Phosphorylation PhosphoSitePlus
T868 Phosphorylation PhosphoSitePlus
T870 Phosphorylation PhosphoSitePlus
S876 Phosphorylation PhosphoSitePlus
K887 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T272 Phosphorylation HPRD 20068231
S274 Phosphorylation HPRD 20068231
S279 Phosphorylation HPRD 20068231
S876 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S13 R13 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
T212 S212 Biomuta DOID:184 / bone cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
T251 N251 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y393 H393 Biomuta DOID:1612 / breast cancer [ cosmic ]
K674 T674 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K700 T700 Biomuta DOID:9256 / colorectal cancer [ cosmic ]