iPTMnet Report for Q8NB49 (ATP11C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8NB49 / AT11C_HUMAN
Protein Name Phospholipid-transporting ATPase IG
Gene Name Name: ATP11C
Synonyms:ATPIG,ATPIQ;
Organism Homo sapiens (Human)

PRO ID PR:Q8NB49
DAG View
PRO Name phospholipid-transporting ATPase IG (human)
Definition A phospholipid-transporting ATPase IG that is encoded in the genome of human.
Short Label hATP11C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8NB49 (ATP11C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y38 Phosphorylation PhosphoSitePlus
Y129 Phosphorylation PhosphoSitePlus
Y231 Phosphorylation PhosphoSitePlus
S232 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
Y261 Phosphorylation PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
T345 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
T365 Phosphorylation PhosphoSitePlus
K433 Ubiquitination PhosphoSitePlus
Y434 Phosphorylation PhosphoSitePlus
K435 Ubiquitination PhosphoSitePlus
T438 Phosphorylation PhosphoSitePlus
S445 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17525332
T447 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T450 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation PhosphoSitePlus
K456 Ubiquitination PhosphoSitePlus
T493 Phosphorylation PhosphoSitePlus
Y494 Phosphorylation PhosphoSitePlus
K506 Ubiquitination PhosphoSitePlus
T540 Phosphorylation PhosphoSitePlus
K566 Ubiquitination PhosphoSitePlus
K585 Ubiquitination PhosphoSitePlus
K604 Ubiquitination PhosphoSitePlus
K622 Ubiquitination PhosphoSitePlus
K654 Ubiquitination PhosphoSitePlus
K706 Ubiquitination PhosphoSitePlus
S736 Phosphorylation PhosphoSitePlus
S739 Phosphorylation PhosphoSitePlus
K854 Ubiquitination PhosphoSitePlus
S1108 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
S1110 Phosphorylation PhosphoSitePlus
S1112 Phosphorylation PhosphoSitePlus
S1116 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 29123098, 18669648, 23186163
T1124 Phosphorylation PhosphoSitePlus
S1126 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 29123098, 18669648, 23186163
S1129 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S361 Phosphorylation HPRD 20068231
T365 Phosphorylation HPRD 20068231
S445 Phosphorylation HPRD 19413330, 18077418, 17525332, ...19664994, 18669648
T447 Phosphorylation HPRD 18669648
S1108 Phosphorylation HPRD 19651622, 18669648, 20068231
S1116 Phosphorylation HPRD 18669648
T1124 Phosphorylation HPRD 20068231
S1126 Phosphorylation HPRD 18669648, 20068231
S1129 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
S361 Phosphorylation HPRD 20068231
T365 Phosphorylation HPRD 20068231
S445 Phosphorylation HPRD 19413330, 18077418, 17525332, ...19664994, 18669648
T447 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y38 N38 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S232 G232 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S232 N232 Biomuta DOID:363 / uterine cancer [ icgc ]
S234 I234 Biomuta DOID:363 / uterine cancer [ icgc ]
K330 N330 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T345 A345 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K854 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S1108 F1108 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S1110 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
S1116 L1116 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1116 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ]