iPTMnet Report for Q8N9N7 (LRRC57)
Protein Information
UniProt AC / UniProt ID | Q8N9N7 / LRC57_HUMAN |
Protein Name | Leucine-rich repeat-containing protein 57 |
Gene Name | Name: LRRC57 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8N9N7 |
PRO Name | leucine-rich repeat-containing protein 57 (human) |
Definition | A leucine-rich repeat-containing protein 57 that is encoded in the genome of human. |
Short Label | hLRRC57 |
Category | organism-gene |
Q8N9N7 (LRRC57) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
G2 | Myristoylation | score1 | UniProt | 25255805 | ||
K15 | Ubiquitination | score1 | PhosphoSitePlus | |||
T16 | Phosphorylation | score1 | PhosphoSitePlus | |||
K22 | Ubiquitination | score1 | PhosphoSitePlus | |||
K35 | Ubiquitination | score1 | PhosphoSitePlus | |||
T37 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S38 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
T42 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S46 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K49 | Ubiquitination | score1 | PhosphoSitePlus | |||
S52 | Phosphorylation | score1 | PhosphoSitePlus | |||
K60 | Ubiquitination | score1 | PhosphoSitePlus | |||
T62 | Phosphorylation | score1 | PhosphoSitePlus | |||
K85 | Ubiquitination | score1 | PhosphoSitePlus | |||
K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
K140 | Ubiquitination | score1 | PhosphoSitePlus | |||
C175 | Methylation | score1 | IEDB | 31844290 | ||
K226 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T16 | I16 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
K35 | N35 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T37 | M37 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K60 | N60 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |