iPTMnet Report for Q8N8A6 (DDX51)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N8A6 / DDX51_HUMAN
Protein Name ATP-dependent RNA helicase DDX51
Gene Name Name: DDX51
Organism Homo sapiens (Human)

PRO ID PR:Q8N8A6
DAG View
PRO Name ATP-dependent RNA helicase DDX51 (human)
Definition An ATP-dependent RNA helicase DDX51 that is encoded in the genome of human.
Short Label hDDX51
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N8A6 (DDX51) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22223895
R8 Methylation PhosphoSitePlus
R30 Methylation PhosphoSitePlus
T64 Phosphorylation PhosphoSitePlus
S83 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 21406692, ...23186163, 17081983, 19664994, 15302935, 19664995, 19007248, 19651622, 18669648, 19690332, 24275569, 18452278, 19415658, 20068231, 19691289
S103 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19007248
S138 Phosphorylation PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
C238 Methylation IEDB 31844290
S255 Phosphorylation HPRD 20068231
K291 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
T435 Phosphorylation HPRD   PhosphoSitePlus 19664994, 20068231
K440 Ubiquitination PhosphoSitePlus
C486 Methylation IEDB 31844290
T562 Phosphorylation HPRD 20068231
Y585 Phosphorylation PhosphoSitePlus
T588 Phosphorylation PhosphoSitePlus
T596 Phosphorylation PhosphoSitePlus
K601 Ubiquitination PhosphoSitePlus
K637 Ubiquitination PhosphoSitePlus
K658 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S255 F255 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K323 * Biomuta DOID:1324 / lung cancer [ cosmic ]
K323 T323 Biomuta DOID:5158 / pleural cancer [ cosmic ]
T588 A588 Biomuta DOID:363 / uterine cancer [ icgc ]