iPTMnet Report for Q8N715 (CCDC185)
Protein Information
UniProt AC / UniProt ID | Q8N715 / CC185_HUMAN |
Protein Name | Coiled-coil domain-containing protein 185 |
Gene Name | Name: CCDC185 Synonyms:C1orf65; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8N715 |
PRO Name | coiled-coil domain-containing protein 185 (human) |
Definition | A protein that is a translation product of the CCDC185 gene in human. |
Short Label | hCCDC185 |
Category | organism-gene |
Q8N715 (CCDC185) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S186 | Phosphorylation | score1 | PhosphoSitePlus | |||
S190 | Phosphorylation | score1 | PhosphoSitePlus | |||
S193 | Phosphorylation | score1 | PhosphoSitePlus | |||
S194 | Phosphorylation | score1 | PhosphoSitePlus | |||
S197 | Phosphorylation | score1 | PhosphoSitePlus | |||
S324 | Phosphorylation | score1 | PhosphoSitePlus | |||
S334 | Phosphorylation | score1 | PhosphoSitePlus | |||
K384 | Ubiquitination | score1 | PhosphoSitePlus | |||
S426 | Phosphorylation | score1 | PhosphoSitePlus | |||
R515 | Methylation | score1 | PhosphoSitePlus | |||
K528 | Sumoylation | score1 | PhosphoSitePlus | |||
K568 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S186 | F186 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S186 | T186 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
S190 | W190 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
S197 | W197 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S197 | L197 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] | |
R515 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R515 | G515 | Biomuta | DOID:263 / kidney cancer [ cosmic ] | |
K568 | M568 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |