Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N6U8 / GP161_HUMAN
Protein Name G-protein coupled receptor 161
Gene Name Name: GPR161
Organism Homo sapiens (Human)

PRO ID PR:Q8N6U8
DAG View
PRO Name G-protein coupled receptor 161 (human)
Definition A G-protein coupled receptor 161 that is encoded in the genome of human.
Short Label hGPR161
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N6U8 (GPR161) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y57 Phosphorylation PhosphoSitePlus
T226 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus
S251 Phosphorylation PhosphoSitePlus
Y344 Phosphorylation PhosphoSitePlus
Y345 Phosphorylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
K441 Ubiquitination PhosphoSitePlus
T490 Phosphorylation PhosphoSitePlus
T493 Phosphorylation PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S245 T245 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S251 G251 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S360 C360 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S430 L430 Biomuta DOID:263 / kidney cancer [ cosmic ]
K441 R441 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T490 I490 Biomuta DOID:9256 / colorectal cancer [ cosmic ]