iPTMnet Report for Q8N6Q8 (METTL25)
Protein Information
UniProt AC / UniProt ID | Q8N6Q8 / MET25_HUMAN |
Protein Name | Probable methyltransferase-like protein 25 |
Gene Name | Name: METTL25 Synonyms:C12orf26; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8N6Q8 |
PRO Name | probable methyltransferase-like protein 25 (human) |
Definition | A probable methyltransferase-like protein 25 that is encoded in the genome of human. |
Short Label | hMETTL25 |
Category | organism-gene |
Q8N6Q8 (METTL25) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y172 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y173 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y187 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y196 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y201 | Phosphorylation | score1 | PhosphoSitePlus | |||
K255 | Ubiquitination | score1 | PhosphoSitePlus | |||
S265 | Phosphorylation | score1 | PhosphoSitePlus | |||
T347 | Phosphorylation | score1 | PhosphoSitePlus | |||
S350 | Phosphorylation | score1 | PhosphoSitePlus | |||
S367 | Phosphorylation | score1 | PhosphoSitePlus | |||
C408 | Methylation | score1 | IEDB | 31844290 | ||
K583 | Acetylation | score1 | PhosphoSitePlus | |||
K583 | Ubiquitination | score1 | PhosphoSitePlus | |||
K589 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y172 | C172 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y187 | * | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
C408 | F408 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K583 | R583 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |