iPTMnet Report for Q8N5C7 (DTWD1)
Protein Information
UniProt AC / UniProt ID | Q8N5C7 / DTWD1_HUMAN |
Protein Name | tRNA-uridine aminocarboxypropyltransferase 1 |
Gene Name | Name: DTWD1 ORFNames:MDS009; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8N5C7 |
PRO Name | tRNA-uridine aminocarboxypropyltransferase 1 (human) |
Definition | A tRNA-uridine aminocarboxypropyltransferase 1 that is encoded in the genome of human. |
Short Label | hDTWD1 |
Category | organism-gene |
Q8N5C7 (DTWD1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 22814378 | ||
K10 | Methylation | score1 | PhosphoSitePlus | |||
K10 | Sumoylation | score1 | PhosphoSitePlus | |||
K18 | Acetylation | score1 | PhosphoSitePlus | |||
K18 | Ubiquitination | score1 | PhosphoSitePlus | |||
K97 | Acetylation | score1 | PhosphoSitePlus | |||
K97 | Ubiquitination | score1 | PhosphoSitePlus | |||
K105 | Acetylation | score1 | PhosphoSitePlus | |||
K105 | Ubiquitination | score1 | PhosphoSitePlus | |||
K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
T181 | Phosphorylation | score1 | PhosphoSitePlus | |||
S192 | Phosphorylation | score1 | PhosphoSitePlus | |||
K193 | Ubiquitination | score1 | PhosphoSitePlus | |||
K269 | Sumoylation | score1 | PhosphoSitePlus | |||
Y270 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K18 | T18 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
K105 | R105 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y270 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |