iPTMnet Report for Q8N3Y3 (LARGE2)
Protein Information
UniProt AC / UniProt ID | Q8N3Y3 / LARG2_HUMAN |
Protein Name | Xylosyl- and glucuronyltransferase LARGE2 |
Gene Name | Name: LARGE2 Synonyms:GYLTL1B;ORFNames:PP5656; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8N3Y3 |
PRO Name | xylosyl- and glucuronyltransferase LARGE2 (human) |
Definition | A xylosyl- and glucuronyltransferase LARGE2 that is encoded in the genome of human. |
Short Label | hLARGE2 |
Category | organism-gene |
Q8N3Y3 (LARGE2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N80 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
S679 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20166139 | ||
T681 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20166139 | ||
Y682 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20166139 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T681 | A681 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
Y682 | H682 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |