iPTMnet Report for Q8N3X1 (FNBP4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N3X1 / FNBP4_HUMAN
Protein Name Formin-binding protein 4
Gene Name Name: FNBP4
Synonyms:FBP30,KIAA1014;
Organism Homo sapiens (Human)

PRO ID PR:Q8N3X1
DAG View
PRO Name formin-binding protein 4 (human)
Definition A formin-binding protein 4 that is encoded in the genome of human.
Short Label hFNBP4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N3X1 (FNBP4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983, ...20068231
S67 Phosphorylation PhosphoSitePlus
S70 Phosphorylation PhosphoSitePlus
S72 Phosphorylation PhosphoSitePlus
Y113 Phosphorylation PhosphoSitePlus
S116 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
T172 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17081983
S285 Phosphorylation PhosphoSitePlus
K301 Sumoylation PhosphoSitePlus
K302 Acetylation PhosphoSitePlus
S314 Phosphorylation PhosphoSitePlus
S324 Phosphorylation PhosphoSitePlus
K348 Acetylation PhosphoSitePlus
K348 Sumoylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
S429 Phosphorylation PhosphoSitePlus
S431 Phosphorylation PhosphoSitePlus
S432 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 16964243, ...15302935, 18669648, 19690332, 20068231, 17081983
S435 Phosphorylation PhosphoSitePlus   UniProt 19690332
S438 Phosphorylation PhosphoSitePlus
S442 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S451 Phosphorylation PhosphoSitePlus
S464 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 20068231
T475 Phosphorylation PhosphoSitePlus
T479 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
T485 Phosphorylation PhosphoSitePlus
S499 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 15302935, ...18669648, 19690332
S508 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...15302935, 18669648, 20068231
T516 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17287340, 18669648, 23186163
T517 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K519 Sumoylation PhosphoSitePlus
K527 Ubiquitination PhosphoSitePlus
K581 Ubiquitination PhosphoSitePlus
T597 Phosphorylation PhosphoSitePlus
K599 Ubiquitination PhosphoSitePlus
S636 Phosphorylation PhosphoSitePlus
T669 Phosphorylation phospho.ELM 15302935
S671 Phosphorylation PhosphoSitePlus
C673 S-Nitrosylation dbSNO 26338901
S676 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
S678 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
S682 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
S683 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
S685 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
T690 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
S764 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
T768 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
T794 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
T794 Phosphorylation PhosphoSitePlus
S797 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 33214551, 35138101, ...35254053, 34846842, 30379171, 32574038, 34725712, 35132862, 28657654, 30059200, 34019948, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
T798 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
S804 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
S809 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
S810 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
T821 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
T833 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
T839 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
S843 O-Glycosylation GlyGen 23301498, 34846842, 33214551, ...35138101, 35254053, 30379171, 32574038, 34725712, 34019948, 28657654, 30059200, 35132862, 30620550, 31492838, 32119511, 35289036, 29351928, 31373491, 29237092, 20068230
S857 Phosphorylation PhosphoSitePlus
S939 Phosphorylation PhosphoSitePlus
S945 Phosphorylation PhosphoSitePlus
K949 Acetylation PhosphoSitePlus
S952 Phosphorylation PhosphoSitePlus
S963 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S964 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S965 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S966 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation HPRD 17081983, 18767875, 20058876, ...19651622, 18669648, 20068231, 17924679
Y113 Phosphorylation HPRD 19413330
S116 Phosphorylation HPRD 19413330, 18669648, 19415658, ...20068231, 18452278
T172 Phosphorylation HPRD 17081983, 18452278
S427 Phosphorylation HPRD 19651622
S429 Phosphorylation HPRD 20068231
S431 Phosphorylation HPRD 20068231
S432 Phosphorylation HPRD 19413330, 16964243, 18767875, ...15302935, 19664995, 18452278, 19651622, 19664994, 18669648, 19415658, 20068231
S442 Phosphorylation HPRD 17525332
S464 Phosphorylation HPRD 15302935, 20068231
T475 Phosphorylation HPRD 18452278
T479 Phosphorylation HPRD 19651622, 19664995, 20068231, ...18452278
T485 Phosphorylation HPRD 18452278
S499 Phosphorylation HPRD 19413330, 18767875, 15302935, ...18452278, 19651622, 18669648, 20068231
S508 Phosphorylation HPRD 19413330, 18767875, 15302935, ...18452278, 19651622, 18669648, 20068231
T516 Phosphorylation HPRD 18669648, 17287340, 20068231
T517 Phosphorylation HPRD 18669648, 20068231
S963 Phosphorylation HPRD 18669648
S964 Phosphorylation HPRD 18669648
S965 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S70 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
Y113 H113 Biomuta DOID:4159 / skin cancer [ cosmic ]
S116 I116 Biomuta DOID:3571 / liver cancer [ cosmic ]
S285 Y285 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S285 F285 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S324 L324 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S451 C451 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S451 F451 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S464 N464 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S499 L499 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ]
S508 F508 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
T517 I517 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T597 I597 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T669 K669 Biomuta DOID:3571 / liver cancer [ cosmic ]
S676 F676 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S678 F678 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T794 K794 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S945 F945 Biomuta [ cosmic ]
S945 C945 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S963 F963 Biomuta DOID:363 / uterine cancer [ icgc ]
S963 Y963 Biomuta DOID:3571 / liver cancer [ cosmic ]
S965 F965 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]