iPTMnet Report for Q8N1G4 (LRRC47)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N1G4 / LRC47_HUMAN
Protein Name Leucine-rich repeat-containing protein 47
Gene Name Name: LRRC47
Synonyms:KIAA1185;
Organism Homo sapiens (Human)

PRO ID PR:Q8N1G4
DAG View
PRO Name leucine-rich repeat-containing protein 47 (human)
Definition A leucine-rich repeat-containing protein 47 that is encoded in the genome of human.
Short Label hLRRC47
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N1G4 (LRRC47) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22223895
Y54 Phosphorylation PhosphoSitePlus
C60 Methylation IEDB 31844290
S92 Phosphorylation PhosphoSitePlus
C190 Methylation IEDB 31844290
S215 O-Glycosylation GlyGen 23301498, 35008409, 33214551, ...29351928, 34019948, 28510447
K226 Ubiquitination PhosphoSitePlus
K228 Ubiquitination PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
Y257 Phosphorylation PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus   UniProt 23186163
R333 Methylation PhosphoSitePlus
Y335 Phosphorylation PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
S431 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 21406692, 17322306, ...24275569, 20068231, 17924679
S433 O-Glycosylation GlyGen 23301498, 35008409, 33214551, ...29351928, 34019948, 28510447
S433 Phosphorylation PhosphoSitePlus
K502 Ubiquitination PhosphoSitePlus
Y509 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
T510 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S518 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 20166139, ...24275569
S520 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 17081983, ...20058876, 18452278, 19651622, 18669648, 24275569, 19690332, 20068231
T522 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19413330, 17081983, 18452278, ...18669648, 20068231
S528 Phosphorylation PhosphoSitePlus
T535 Phosphorylation PhosphoSitePlus
S561 Phosphorylation PhosphoSitePlus
K569 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K228 T228 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R333 Q333 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R333 W333 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ icgc ]
K369 N369 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S431 R431 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S431 C431 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K502 T502 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K502 N502 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]