iPTMnet Report for Q8N196 (SIX5)
Protein Information
UniProt AC / UniProt ID | Q8N196 / SIX5_HUMAN |
Protein Name | Homeobox protein SIX5 |
Gene Name | Name: SIX5 Synonyms:DMAHP; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8N196 |
PRO Name | homeobox protein SIX5 (human) |
Definition | A homeobox protein SIX5 that is encoded in the genome of human. |
Short Label | hSIX5 |
Category | organism-gene |
Q8N196 (SIX5) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S66 | Phosphorylation | score1 | PhosphoSitePlus | |||
S72 | Phosphorylation | score1 | PhosphoSitePlus | |||
R121 | Methylation | score1 | PhosphoSitePlus | |||
S123 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y140 | Phosphorylation | score1 | PhosphoSitePlus | |||
R168 | Methylation | score1 | PhosphoSitePlus | |||
K209 | Ubiquitination | score1 | PhosphoSitePlus | |||
T275 | Phosphorylation | score1 | PhosphoSitePlus | |||
T276 | Phosphorylation | score1 | PhosphoSitePlus | |||
S354 | Phosphorylation | score1 | PhosphoSitePlus | |||
S355 | Phosphorylation | score1 | PhosphoSitePlus | |||
T380 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S66 | F66 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
R121 | S121 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
R121 | H121 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
T380 | A380 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |