iPTMnet Report for Q8N108 (MIER1)
Protein Information
UniProt AC / UniProt ID | Q8N108 / MIER1_HUMAN |
Protein Name | Mesoderm induction early response protein 1 |
Gene Name | Name: MIER1 Synonyms:KIAA1610; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8N108 |
PRO Name | mesoderm induction early response protein 1 (human) |
Definition | A mesoderm induction early response protein 1 that is encoded in the genome of human. |
Short Label | hMIER1 |
Category | organism-gene |
Q8N108 (MIER1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S10 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
T38 | Phosphorylation | score1 | PhosphoSitePlus | |||
S52 | Phosphorylation | score1 | PhosphoSitePlus | |||
S53 | Phosphorylation | score1 | PhosphoSitePlus | |||
S71 | Phosphorylation | score1 | PhosphoSitePlus | |||
S77 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
S121 | Phosphorylation | score1 | PhosphoSitePlus | |||
S122 | Phosphorylation | score1 | PhosphoSitePlus | |||
S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
S131 | Phosphorylation | score1 | PhosphoSitePlus | |||
S141 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
Y155 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 | ||
T158 | Phosphorylation | score1 | PhosphoSitePlus | |||
S160 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 21406692, 19690332 | ||
S166 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 21406692, 20068231, ... | ||
Y172 | Phosphorylation | score1 | PhosphoSitePlus | |||
C197 | Methylation | score1 | IEDB | 31844290 | ||
K223 | Ubiquitination | score1 | PhosphoSitePlus | |||
K239 | Ubiquitination | score1 | PhosphoSitePlus | |||
K251 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y258 | Phosphorylation | score1 | PhosphoSitePlus | |||
K262 | Ubiquitination | score1 | PhosphoSitePlus | |||
K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
S367 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S369 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S372 | Phosphorylation | score1 | PhosphoSitePlus | |||
S373 | Phosphorylation | score1 | PhosphoSitePlus | |||
S377 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
T381 | Phosphorylation | score1 | PhosphoSitePlus | |||
S383 | Phosphorylation | score1 | PhosphoSitePlus | |||
S407 | Phosphorylation | score1 | phospho.ELM | 15302935 | ||
K420 | Sumoylation | score1 | PhosphoSitePlus | |||
T448 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S483 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163, 21406692, ... | ||
S488 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 23186163, 21406692, ... | ||
S491 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S492 | Phosphorylation | score1 | PhosphoSitePlus | |||
T510 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S52 | Phosphorylation | score0 | HPRD | 18669648 | ||
S53 | Phosphorylation | score0 | HPRD | 18669648 | ||
S121 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
S122 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
T128 | Phosphorylation | score0 | HPRD | 17081983 | ||
S130 | Phosphorylation | score0 | HPRD | 18452278 | ||
S131 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
S141 | Phosphorylation | score0 | HPRD | 18077418 | ||
Y155 | Phosphorylation | score0 | HPRD | 18669648, 17081983 | ||
T158 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 18452278 | ||
S160 | Phosphorylation | score0 | HPRD | 19413330, 17081983, 18452278, ... | ||
S166 | Phosphorylation | score0 | HPRD | 19413330, 18452278, 19651622, ... | ||
S367 | Phosphorylation | score0 | HPRD | 19691289, 20068231 | ||
S369 | Phosphorylation | score0 | HPRD | 17081983, 20068231, 19691289 | ||
S372 | Phosphorylation | score0 | HPRD | 17081983 | ||
S373 | Phosphorylation | score0 | HPRD | 19007248 | ||
S377 | Phosphorylation | score0 | HPRD | 19664994, 19691289, 20068231 | ||
S483 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
S488 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 17081983, ... | ||
S491 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
S492 | Phosphorylation | score0 | HPRD | 17081983 | ||
S500 | Phosphorylation | score0 | HPRD | 17081983 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S105 | Phosphorylation | score0 | HPRD | 18669648 | ||
S106 | Phosphorylation | score0 | HPRD | 18669648 | ||
S174 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
S175 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
T181 | Phosphorylation | score0 | HPRD | 17081983 | ||
S183 | Phosphorylation | score0 | HPRD | 18452278 | ||
S184 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
S194 | Phosphorylation | score0 | HPRD | 18077418 | ||
Y208 | Phosphorylation | score0 | HPRD | 18669648, 17081983 | ||
T211 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 18452278 | ||
S213 | Phosphorylation | score0 | HPRD | 19413330, 17081983, 18452278, ... | ||
S219 | Phosphorylation | score0 | HPRD | 19413330, 18452278, 19651622, ... | ||
S420 | Phosphorylation | score0 | HPRD | 19691289, 20068231 | ||
S422 | Phosphorylation | score0 | HPRD | 17081983, 20068231, 19691289 | ||
S425 | Phosphorylation | score0 | HPRD | 17081983 | ||
S426 | Phosphorylation | score0 | HPRD | 19007248 | ||
S430 | Phosphorylation | score0 | HPRD | 19664994, 19691289, 20068231 | ||
S536 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231 | ||
S541 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 17081983, ... | ||
S544 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
S545 | Phosphorylation | score0 | HPRD | 17081983 | ||
S553 | Phosphorylation | score0 | HPRD | 17081983 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S69 | Phosphorylation | score0 | HPRD | 18669648 | ||
S70 | Phosphorylation | score0 | HPRD | 18669648 | ||
S138 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
S139 | Phosphorylation | score0 | HPRD | 15302935, 18452278 | ||
S147 | Phosphorylation | score0 | HPRD | 18452278 | ||
S148 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
S158 | Phosphorylation | score0 | HPRD | 18077418 | ||
Y172 | Phosphorylation | score0 | HPRD | 18669648, 17081983 | ||
T175 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 18452278 | ||
S177 | Phosphorylation | score0 | HPRD | 19413330, 17081983, 18452278, ... | ||
S183 | Phosphorylation | score0 | HPRD | 19413330, 15302935, 18452278, ... | ||
S384 | Phosphorylation | score0 | HPRD | 19691289, 20068231 | ||
S386 | Phosphorylation | score0 | HPRD | 17081983, 20068231, 19691289 | ||
S389 | Phosphorylation | score0 | HPRD | 17081983 | ||
S390 | Phosphorylation | score0 | HPRD | 19007248 | ||
S394 | Phosphorylation | score0 | HPRD | 15302935, 19664994, 19691289, ... | ||
T398 | Phosphorylation | score0 | HPRD | 15302935 | ||
S400 | Phosphorylation | score0 | HPRD | 15302935 | ||
S500 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231, ... | ||
S505 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 20068231, ... | ||
S508 | Phosphorylation | score0 | HPRD | 19651622, 20068231 | ||
S509 | Phosphorylation | score0 | HPRD | 17081983 | ||
S517 | Phosphorylation | score0 | HPRD | 17081983 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S69 | Phosphorylation | score0 | HPRD | 18669648 | ||
S70 | Phosphorylation | score0 | HPRD | 18669648 | ||
S138 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
S139 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
S147 | Phosphorylation | score0 | HPRD | 18452278 | ||
S148 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
S158 | Phosphorylation | score0 | HPRD | 18077418 | ||
Y172 | Phosphorylation | score0 | HPRD | 18669648, 17081983 | ||
T175 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 18452278 | ||
S177 | Phosphorylation | score0 | HPRD | 19413330, 17081983, 18452278, ... | ||
S183 | Phosphorylation | score0 | HPRD | 19413330, 18452278, 19651622, ... | ||
S384 | Phosphorylation | score0 | HPRD | 19691289, 20068231 | ||
S386 | Phosphorylation | score0 | HPRD | 17081983, 20068231, 19691289 | ||
S389 | Phosphorylation | score0 | HPRD | 17081983 | ||
S390 | Phosphorylation | score0 | HPRD | 19007248 | ||
S394 | Phosphorylation | score0 | HPRD | 19664994, 19691289, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S105 | Phosphorylation | score0 | HPRD | 18669648 | ||
S106 | Phosphorylation | score0 | HPRD | 18669648 | ||
S174 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
S175 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
T181 | Phosphorylation | score0 | HPRD | 17081983 | ||
S183 | Phosphorylation | score0 | HPRD | 18452278 | ||
S184 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
S194 | Phosphorylation | score0 | HPRD | 18077418 | ||
Y208 | Phosphorylation | score0 | HPRD | 18669648, 17081983 | ||
T211 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 18452278 | ||
S213 | Phosphorylation | score0 | HPRD | 19413330, 17081983, 18452278, ... | ||
S219 | Phosphorylation | score0 | HPRD | 19413330, 18452278, 19651622, ... | ||
S420 | Phosphorylation | score0 | HPRD | 19691289, 20068231 | ||
S422 | Phosphorylation | score0 | HPRD | 17081983, 20068231, 19691289 | ||
S425 | Phosphorylation | score0 | HPRD | 17081983 | ||
S426 | Phosphorylation | score0 | HPRD | 19007248 | ||
S430 | Phosphorylation | score0 | HPRD | 19664994, 19691289, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S52 | Phosphorylation | score0 | HPRD | 18669648 | ||
S53 | Phosphorylation | score0 | HPRD | 18669648 | ||
S121 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
S122 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
T128 | Phosphorylation | score0 | HPRD | 17081983 | ||
S130 | Phosphorylation | score0 | HPRD | 18452278 | ||
S131 | Phosphorylation | score0 | HPRD | 17081983, 18452278 | ||
S141 | Phosphorylation | score0 | HPRD | 18077418 | ||
Y155 | Phosphorylation | score0 | HPRD | 18669648, 17081983 | ||
T158 | Phosphorylation | score0 | HPRD | 18669648, 20068231, 18452278 | ||
S160 | Phosphorylation | score0 | HPRD | 19413330, 17081983, 18452278, ... | ||
S166 | Phosphorylation | score0 | HPRD | 19413330, 18452278, 19651622, ... | ||
S367 | Phosphorylation | score0 | HPRD | 19691289, 20068231 | ||
S369 | Phosphorylation | score0 | HPRD | 17081983, 20068231, 19691289 | ||
S372 | Phosphorylation | score0 | HPRD | 17081983 | ||
S373 | Phosphorylation | score0 | HPRD | 19007248 | ||
S377 | Phosphorylation | score0 | HPRD | 19664994, 19691289, 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S10 | C10 | Biomuta | DOID:5041 / esophageal cancer [ cosmic, icgc ] | |
T38 | A38 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S130 | F130 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S147 | F147 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
Y155 | D155 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
Y172 | D172 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc, cosmic, icgc, cosmic, icgc, cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc, cosmic, icgc, cosmic, icgc ] | |
S183 | F183 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
Y208 | D208 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K251 | E251 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S407 | P407 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |