iPTMnet Report for Q8N0Z6 (TTC5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8N0Z6 / TTC5_HUMAN
Protein Name Tetratricopeptide repeat protein 5
Gene Name Name: TTC5
Organism Homo sapiens (Human)

PRO ID PR:Q8N0Z6
DAG View
PRO Name tetratricopeptide repeat protein 5 (human)
Definition A tetratricopeptide repeat protein 5 that is encoded in the genome of human.
Short Label hTTC5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8N0Z6 (TTC5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K52 Ubiquitination PhosphoSitePlus
T74 O-Glycosylation GlyGen 23301498, 30379171
K76 Ubiquitination PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
K94 Ubiquitination PhosphoSitePlus
K97 Sumoylation PhosphoSitePlus
K97 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
Y193 Phosphorylation PhosphoSitePlus
S203 Phosphorylation Q13315 (ATM) neXtProt   PRO   Signor 15448695
K215 Ubiquitination PhosphoSitePlus
S221 Phosphorylation PRO
K235 Ubiquitination PhosphoSitePlus
Y236 Phosphorylation PhosphoSitePlus
K288 Ubiquitination PhosphoSitePlus
K322 Sumoylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000049560 (hTTC5/Phos:1) pS203 PRO
PR:000049561 (hTTC5/Phos:2) pS203,pS221 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S221 C221 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K401 T401 Biomuta DOID:9256 / colorectal cancer [ cosmic ]