Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IZF3 / AGRF4_HUMAN
Protein Name Adhesion G protein-coupled receptor F4 precursor
Gene Name Name: ADGRF4
Synonyms:GPR115,PGR18;
Organism Homo sapiens (Human)

PRO ID PR:Q8IZF3
DAG View
PRO Name adhesion G protein-coupled receptor F4 (human)
Definition An adhesion G protein-coupled receptor F4 that is encoded in the genome of human.
Short Label hADGRF4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IZF3 (ADGRF4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K4 Ubiquitination PhosphoSitePlus
T45 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
S60 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus
T381 Phosphorylation PhosphoSitePlus
Y500 Phosphorylation PhosphoSitePlus
S681 Phosphorylation PhosphoSitePlus
T685 Phosphorylation PhosphoSitePlus
S688 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T45 I45 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S60 F60 Biomuta DOID:4159 / skin cancer [ cosmic ]
S288 Y288 Biomuta DOID:1324 / lung cancer [ cosmic ]
S288 F288 Biomuta DOID:4159 / skin cancer [ cosmic ]
S322 L322 Biomuta DOID:4159 / skin cancer [ cosmic ]
S688 C688 Biomuta DOID:1324 / lung cancer [ cosmic ]