iPTMnet Report Q8IZ73 RPUSD2

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q8IZ73 / RUSD2_HUMAN
Protein Name	Pseudouridylate synthase RPUSD2
Gene Name	Name: RPUSD2 Synonyms:C15orf19;
Organism	Homo sapiens (Human)

PRO ID	PR:Q8IZ73 DAG View
PRO Name	pseudouridylate synthase RPUSD2 (human)
Definition	A pseudouridylate synthase RPUSD2 that is encoded in the genome of human.
Short Label	hRPUSD2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q8IZ73 (RPUSD2) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S29	Phosphorylation		score1	PhosphoSitePlus
	S68	Phosphorylation		score2	phospho.ELM PhosphoSitePlus UniProt	18669648, 23186163, 20068231
	S90	Phosphorylation		score1	PhosphoSitePlus
	K192	Ubiquitination		score1	PhosphoSitePlus
	K265	Ubiquitination		score1	PhosphoSitePlus
	S290	Phosphorylation		score1	PhosphoSitePlus
	K304	Acetylation		score1	PhosphoSitePlus
	K304	Ubiquitination		score1	PhosphoSitePlus
	K422	Ubiquitination		score1	PhosphoSitePlus
	S436	Phosphorylation		score1	PhosphoSitePlus

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S68	Phosphorylation		score0	HPRD	19651622, 18669648, 19664995, ...20068231, 17924679

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
S290	F290	Biomuta		DOID:4159 / skin cancer [ cosmic, icgc ]
S290	T290	Biomuta		DOID:3571 / liver cancer [ cosmic ]