iPTMnet Report for Q8IYB8 (SUPV3L1)
Protein Information
UniProt AC / UniProt ID | Q8IYB8 / SUV3_HUMAN |
Protein Name | ATP-dependent RNA helicase SUPV3L1, mitochondrial precursor |
Gene Name | Name: SUPV3L1 Synonyms:SUV3; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q8IYB8 |
PRO Name | ATP-dependent RNA helicase SUPV3L1, mitochondrial (human) |
Definition | An ATP-dependent RNA helicase SUPV3L1, mitochondrial that is encoded in the genome of human. |
Short Label | hSUPV3L1 |
Category | organism-gene |
Q8IYB8 (SUPV3L1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K99 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K201 | Ubiquitination | score1 | PhosphoSitePlus | |||
K213 | Ubiquitination | score1 | PhosphoSitePlus | |||
K220 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
Y379 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y396 | Phosphorylation | score1 | PhosphoSitePlus | |||
S398 | Phosphorylation | score1 | PhosphoSitePlus | |||
T403 | Phosphorylation | score1 | PhosphoSitePlus | |||
T604 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y611 | Phosphorylation | score1 | PhosphoSitePlus | |||
T674 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
K704 | Ubiquitination | score1 | PhosphoSitePlus | |||
K719 | Ubiquitination | score1 | PhosphoSitePlus | |||
S725 | Phosphorylation | P28482 (MAPK1) | score2 | HPRD neXtProt PhosphoSitePlus UniProt | 18669648, 22028470, 23186163 | |
T744 | Phosphorylation | score1 | PhosphoSitePlus | |||
K749 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T604 | P604 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
T604 | A604 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K749 | R749 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] |