iPTMnet Report for Q8IY67 (RAVER1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IY67 / RAVR1_HUMAN
Protein Name Ribonucleoprotein PTB-binding 1
Gene Name Name: RAVER1
Synonyms:KIAA1978;
Organism Homo sapiens (Human)

PRO ID PR:Q8IY67
DAG View
PRO Name ribonucleoprotein PTB-binding 1 (human)
Definition A ribonucleoprotein PTB-binding 1 that is encoded in the genome of human.
Short Label hRAVER1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IY67 (RAVER1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 19369195, 21406692, ...20068231
S6 Phosphorylation PhosphoSitePlus   UniProt 23186163
T8 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus   UniProt 19369195, 21406692, 23186163, ...20068231
K16 Sumoylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
R30 Methylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
Y82 Phosphorylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
Y86 Phosphorylation PhosphoSitePlus
C87 Methylation IEDB 31844290
K91 Ubiquitination PhosphoSitePlus
Y92 Phosphorylation PhosphoSitePlus
C135 Methylation IEDB 31844290
K173 Ubiquitination PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus
K190 Sumoylation PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
T214 Phosphorylation PhosphoSitePlus
C251 Methylation IEDB 31844290
S399 Phosphorylation PhosphoSitePlus
K434 Ubiquitination PhosphoSitePlus
T463 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...16964243, 15302935, 24275569, 19690332, 20068231
R472 Methylation PhosphoSitePlus
S474 Phosphorylation PhosphoSitePlus   UniProt 20068231
R477 Methylation PhosphoSitePlus
P488 Phosphorylation UniProt 18669648, 20068231
K501 Methylation PhosphoSitePlus
K507 Acetylation PhosphoSitePlus
S512 Phosphorylation PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
S524 Phosphorylation PhosphoSitePlus
S531 Phosphorylation PhosphoSitePlus
H567 Phosphorylation UniProt 18691976, 18669648, 21406692, ...20068231
R581 Methylation PhosphoSitePlus
S583 Phosphorylation PhosphoSitePlus
K587 Methylation PhosphoSitePlus
T594 Phosphorylation PhosphoSitePlus
R596 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S17 Phosphorylation phospho.ELM 18669648
T463 Phosphorylation phospho.ELM 18669648
S474 Phosphorylation PhosphoSitePlus
R477 Methylation PhosphoSitePlus
S483 Phosphorylation PhosphoSitePlus
T488 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
K500 Ubiquitination PhosphoSitePlus
Y509 Phosphorylation PhosphoSitePlus
K524 Ubiquitination PhosphoSitePlus
R527 Methylation PhosphoSitePlus
R534 Methylation PhosphoSitePlus
T544 Phosphorylation PhosphoSitePlus
K557 Ubiquitination PhosphoSitePlus
K562 Methylation PhosphoSitePlus
K562 Sumoylation PhosphoSitePlus
K562 Ubiquitination PhosphoSitePlus
R564 Methylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
S570 Phosphorylation PhosphoSitePlus
S571 Phosphorylation PhosphoSitePlus
S583 Phosphorylation PhosphoSitePlus
Y588 Phosphorylation PhosphoSitePlus
R595 Methylation PhosphoSitePlus
S599 Phosphorylation PhosphoSitePlus
R602 Methylation PhosphoSitePlus
S612 Phosphorylation PhosphoSitePlus
K615 Sumoylation PhosphoSitePlus
S617 Phosphorylation PhosphoSitePlus
S621 Phosphorylation PhosphoSitePlus
S643 Phosphorylation PhosphoSitePlus
Y647 Phosphorylation PhosphoSitePlus
K657 Methylation PhosphoSitePlus
K657 Ubiquitination PhosphoSitePlus
S680 Phosphorylation PhosphoSitePlus
K698 Sumoylation PhosphoSitePlus
K698 Ubiquitination PhosphoSitePlus
S700 Phosphorylation O14757 (CHEK1) PhosphoSitePlus 21851590
S707 Phosphorylation PhosphoSitePlus
S711 Phosphorylation PhosphoSitePlus
S721 Phosphorylation PhosphoSitePlus
Y728 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T8 I8 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K91 N91 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S185 L185 Biomuta DOID:1324 / lung cancer [ cosmic ]
K190 E190 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S399 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S512 F512 Biomuta DOID:4159 / skin cancer [ cosmic ]
H567 L567 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
R581 H581 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]