iPTMnet Report for Q8IY33 (MICALL2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q8IY33 / MILK2_HUMAN
Protein Name MICAL-like protein 2
Gene Name Name: MICALL2
Synonyms:JRAB;
Organism Homo sapiens (Human)

PRO ID PR:Q8IY33
DAG View
PRO Name MICAL-like protein 2 (human)
Definition A MICAL-like protein 2 that is encoded in the genome of human.
Short Label hMICALL2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q8IY33 (MICALL2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y59 Phosphorylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus   UniProt 23186163
S122 Phosphorylation PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
S143 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 18669648, 23186163, ...24275569
S153 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
T157 Phosphorylation PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus
T221 Phosphorylation PhosphoSitePlus
S249 Phosphorylation PhosphoSitePlus   UniProt 23186163
S272 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus   UniProt 23186163
S299 O-Glycosylation GlyGen 34846842, 31637018, 32574038, ...31492838, 35254053, 35132862, 28657654
T309 O-Glycosylation GlyGen 31637018, 32574038, 32938750, ...31492838, 35254053, 35132862, 28657654
S310 O-Glycosylation GlyGen 31637018, 32574038, 31492838, ...35254053, 35132862, 28657654
T312 O-Glycosylation GlyGen 32574038
S313 O-Glycosylation GlyGen 32574038
S318 Phosphorylation PhosphoSitePlus
T330 Phosphorylation PhosphoSitePlus
T375 Phosphorylation PhosphoSitePlus
T423 Phosphorylation PhosphoSitePlus
S433 Phosphorylation PhosphoSitePlus
R435 Methylation PhosphoSitePlus
S475 Phosphorylation PhosphoSitePlus
T488 O-Glycosylation GlyGen 31637018, 32574038, 31492838, ...35254053, 35132862, 28657654
S494 O-Glycosylation GlyGen 31637018, 32574038, 31492838, ...35254053, 35132862, 28657654
S494 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S504 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S573 Phosphorylation PhosphoSitePlus
S598 Phosphorylation PhosphoSitePlus   UniProt 23186163
S627 Phosphorylation PhosphoSitePlus
T635 Phosphorylation PhosphoSitePlus
T637 Phosphorylation PhosphoSitePlus
T644 Phosphorylation PhosphoSitePlus   UniProt 24275569
S649 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 27869121
S653 Phosphorylation PhosphoSitePlus
S658 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S660 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S693 Phosphorylation PhosphoSitePlus
S712 Phosphorylation PhosphoSitePlus
S726 Phosphorylation PhosphoSitePlus
Y734 Phosphorylation PhosphoSitePlus
S736 Phosphorylation PhosphoSitePlus
S895 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S143 Phosphorylation HPRD 18088087, 18669648, 20058876, ...19664995
S494 Phosphorylation HPRD 18669648
S504 Phosphorylation HPRD 18669648
S649 Phosphorylation HPRD 18669648
S658 Phosphorylation HPRD 18669648
S660 Phosphorylation HPRD 18669648
S726 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S122 L122 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S272 F272 Biomuta DOID:4159 / skin cancer [ cosmic ]
S294 P294 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S310 G310 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S313 F313 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T375 K375 Biomuta DOID:3571 / liver cancer [ cosmic ]
S475 P475 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S494 T494 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S573 R573 Biomuta DOID:4159 / skin cancer [ cosmic ]
T635 I635 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T637 N637 Biomuta DOID:4362 / cervical cancer [ icgc ]
S653 T653 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S726 F726 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S736 F736 Biomuta DOID:4159 / skin cancer [ cosmic ]